117828-38-3Relevant academic research and scientific papers
A Synthetic Approach to Rocaglamide via Reductive Cyclization of δ-Keto Nitriles
Kraus, George A.,Sy, James O.
, p. 77 - 83 (1989)
The anticancer agent rocaglamide contains a novel bicyclooctanol structure.The approach to this molecule involved the preparation of a hydroxy ketone intermediate via a samarium-mediated cyclization.This ketone was then converted into an excellent
