
Journal of Organic Chemistry p. 77 - 83 (1989)
Update date:2022-07-30
Topics:
Kraus, George A.
Sy, James O.
The anticancer agent rocaglamide contains a novel bicyclo<3.3.0>octanol structure.The approach to this molecule involved the preparation of a hydroxy ketone intermediate via a samarium-mediated cyclization.This ketone was then converted into an excellent
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