117836-13-2 Usage
Uses
Used in Pharmaceutical Synthesis:
(S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the formation of complex drug molecules. The presence of functional groups allows for further chemical reactions, facilitating the development of new therapeutic agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester is utilized as a building block for the design and synthesis of bioactive molecules. Its structural features make it suitable for the creation of compounds with potential therapeutic applications.
Used in Drug Discovery:
(S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester is employed as a component in drug discovery processes, where it aids in the identification and development of new drug candidates. Its reactivity and structural attributes are leveraged to explore novel chemical entities with potential medicinal properties.
Used in Chemical Research:
In chemical research, (S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester serves as an important compound for studying reaction mechanisms and exploring new synthetic pathways. Its unique structure provides opportunities for understanding and advancing the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 117836-13-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,8,3 and 6 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 117836-13:
(8*1)+(7*1)+(6*7)+(5*8)+(4*3)+(3*6)+(2*1)+(1*3)=132
132 % 10 = 2
So 117836-13-2 is a valid CAS Registry Number.
117836-13-2Relevant articles and documents
MANUFACTURING METHOD OF (2S,5S)-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID AS WELL AS MANUFACTURING INTERMEDIATE OF THE SAME AND METHOD FOR MANUFACTURING THE SAME
-
, (2016/12/22)
PROBLEM TO BE SOLVED: To provide synthesis methods of 5-hydroxy-6-methoxypiperidine-2-carboxylic acid derivatives and 5-oxopiperidine-2-carboxylic acid derivatives more safely than ever by using inexpensive raw ingredients. SOLUTION: In the provided method, a compound expressed by the following formula [X] is manufactured from a compound expressed by the following formula [I] through steps (1) through (9) [either steps (4) and (5) or steps (6) and (7) in the case of steps (4) through (7)]. COPYRIGHT: (C)2015,JPOandINPIT
An efficient route to the α-methyl ester of L-glutamic acid, and its conversion into cis-5-hydroxy-L-pipecolic acid
Adams, David R.,Bailey, Patrick D.,Collier, Ian D.,Heffernan, John D.,Stokes, Stephen
, p. 349 - 350 (2007/10/03)
The treatment of the N-benzyloxycarbonyl α-methyl esters of L-glutamine or L-asparagine with tert-butyl nitrite in refluxing acetonitrile results in selective hydrolysis of the amide group, giving optically pure Z-Glu-OMe (74%) or Z-Asp-OMe (88%); these are versatile chiral building blocks, and an efficient synthesis of cis-5-hydroxy-L-pipecolic acid from Z-Glu-OMe is described.
Synthesis of 5-oxo-L-pipecolic acid derivatives by rhodium(II) acetate catalyzed cyclization of diazoketones
Ko, Kwang-Youn,Lee, Kee-In,Kim, Wan-Loo
, p. 6651 - 6652 (2007/10/02)
A convenient synthesis of 5-oxo-L-pipecolic acid derivatives is described. The key step involves the rhodium(II) acetate catalysed N-H insertion reaction of diazoketones, which are derived from L-glutamic acid.
