117840-81-0

Basic information

• Product Name: (4-METHYL-THIAZOL-2-YL)-ACETIC ACID METHYL ESTER
• Synonyms: METHYL (4-METHYL-1,3-THIAZOL-2-YL)ACETATE;(4-METHYL-THIAZOL-2-YL)-ACETIC ACID METHYL ESTER;2-Thiazoleacetic acid, 4-Methyl-, Methyl ester;Methyl 2-(4-Methylthiazol-2-yl)acetate
• CAS NO: 117840-81-0
• Molecular Formula: C7H9NO2S
• Molecular Weight: 171.22
• Mol File: 117840-81-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 245.4±23.0 °C(Predicted)
• Appearance: /
• Density: 1.212±0.06 g/cm3(Predicted)
• PKA: 2.78±0.10(Predicted)
• CAS DataBase Reference: (4-METHYL-THIAZOL-2-YL)-ACETIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (4-METHYL-THIAZOL-2-YL)-ACETIC ACID METHYL ESTER(117840-81-0)
• EPA Substance Registry System: (4-METHYL-THIAZOL-2-YL)-ACETIC ACID METHYL ESTER(117840-81-0)

Safety Data

• Hazardous Substances Data: 117840-81-0(Hazardous Substances Data)

Usage

Description

(4-METHYL-THIAZOL-2-YL)-ACETIC ACID METHYL ESTER, with the molecular formula C8H9NO2S, is an ester derivative of thiazole, a five-membered organic heterocyclic compound that contains both sulfur and nitrogen atoms. This versatile chemical compound is widely used in organic synthesis and serves as an intermediate in the production of pharmaceuticals and agrochemicals. Its unique properties and applications make it a valuable building block for synthesizing a variety of organic compounds, and a thorough understanding of this compound is essential for researchers and chemists to harness its potential effectively.

Uses

Used in Organic Synthesis:
(4-METHYL-THIAZOL-2-YL)-ACETIC ACID METHYL ESTER is used as a key intermediate for the synthesis of various organic compounds. Its unique structure allows it to be a versatile building block in the creation of a wide range of chemical products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (4-METHYL-THIAZOL-2-YL)-ACETIC ACID METHYL ESTER is used as an intermediate in the development of new drugs. Its presence in the molecular structure of certain pharmaceuticals contributes to their therapeutic effects and properties.
Used in Agrochemical Production:
Similarly, in the agrochemical sector, (4-METHYL-THIAZOL-2-YL)-ACETIC ACID METHYL ESTER is utilized as an intermediate for the synthesis of various agrochemicals. Its role in the production of these chemicals is crucial for their effectiveness in agricultural applications.
Used in Research and Development:
(4-METHYL-THIAZOL-2-YL)-ACETIC ACID METHYL ESTER is also used in research and development settings, where chemists and researchers explore its potential applications and interactions with other compounds. This helps in discovering new uses and enhancing the understanding of its chemical behavior.

Upstream product

• 67-56-1 methanol 
• 19785-39-8 (4-methylthiazol-2-yl)acetonitrile 

Relevant articles and documents

TRIAZOLE DERIVATIVE OR SALT THEREOF

[Problem] There is provided a compound which can be used for therapy of diseases in which 11 β-hydroxysteroid dehydrogenase type 1(11β-HSD1) participates, in particular diabetes, insulin resistance. [Means for Solution] It has been found that a triazole derivative wherein the triazole ring is substituted with a trisubstituted methyl group in the 2-position or a pharmaceutically acceptable salt thereof has a strong 11β-HSD1 inhibitory activity. Moreover, the triazole derivative of the invention exhibits an excellent blood-glucose level-lowering action and hence can be used for therapy of diabetes, insulin resistance.