1178576-56-1

Basic information

• Product Name: C₁₂H₁₁NO₂
• CAS NO: 1178576-56-1
• Molecular Weight: 201.225
• Mol File: 1178576-56-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₁NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₁NO₂(1178576-56-1)
• EPA Substance Registry System: C₁₂H₁₁NO₂(1178576-56-1)

Safety Data

• Hazardous Substances Data: 1178576-56-1(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 90794-29-9 ethyl 2-(2-iodophenyl)acetate 
• 4042-43-7 (4R)-4-methyl-1,3-oxazolidin-2-one 

Relevant articles and documents

Synthesis of ring-fused oxazolo- and pyrazoloisoquinolinones by a one-pot Pd-catalyzed carboxamidation and aldol-type condensation cascade process

(Chemical Equation Presented) A three-component cascade process is described for the synthesis of ring-fused oxazolo- and pyrazoloisoquinolinones by a one-pot carboxamidation/aldol-type condensation reaction. The cascade process involves Pd-catalyzed carboxamidation of an aryl halide/active methylene compound with oxazolidinone or pyrazolidinone, and subsequent intramolecular base-catalyzed cyclization/dehydration through an aldol-type condensation process, to give ring-fused oxazolo- and pyrazoloisoquinolinones. This methodology provides an easy one-step approach to these important classesof nitrogen-containing heterocycles and can tolerate a wide array of functional groups, including ester, nitrile, methoxy, and halide.