92406-53-6

Basic information

• Product Name: methyl 5-amino-1-methyl-1H-pyrazole-3-carboxylate
• Synonyms: methyl 5-amino-1-methyl-1H-pyrazole-3-carboxylate;5-Amino-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester
• CAS NO: 92406-53-6
• Molecular Formula: C₆H₉N₃O₂
• Molecular Weight: 155.15456
• Mol File: 92406-53-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: 101-102 °C
• Boiling Point: 326.168°C at 760 mmHg
• Flash Point: 151.062°C
• Appearance: /
• Density: 1.351g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.584
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 1.74±0.10(Predicted)
• CAS DataBase Reference: methyl 5-amino-1-methyl-1H-pyrazole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-amino-1-methyl-1H-pyrazole-3-carboxylate(92406-53-6)
• EPA Substance Registry System: methyl 5-amino-1-methyl-1H-pyrazole-3-carboxylate(92406-53-6)

Safety Data

• Hazardous Substances Data: 92406-53-6(Hazardous Substances Data)

Usage

General Description

Methyl 5-amino-1-methyl-1H-pyrazole-3-carboxylate is a chemical compound with the molecular formula C6H8N4O2. It is a pyrazole derivative, which is a five-membered aromatic ring with two nitrogen atoms at positions 1 and 2. methyl 5-amino-1-methyl-1H-pyrazole-3-carboxylate is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has potential applications in the development of new drugs and agricultural products due to its structure and reactivity. Methyl 5-amino-1-methyl-1H-pyrazole-3-carboxylate may also have uses in academic research and chemical manufacturing processes.

InChI:InChI=1/C6H9N3O2/c1-9-5(7)3-4(8-9)6(10)11-2/h3H,7H2,1-2H3

Upstream product

• 181585-93-3 5-nitro-1H-pyrazole-3-carboxylic acid methyl ester 
• 1227409-70-2 methyl 3-cyano-2-sodiumoxy-2-propenoate 
• 302-15-8 methylhydrazine sulfuric acid 
• 796038-07-8 1-methyl-5-nitro-1H-pyrazole-3-carboxylic acid methyl ester 
• 177409-38-0 2-methyl-5-nitro-2H-pyrazole-3-carboxylic acid methyl ester 
• 117860-55-6 3-(methoxycarbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid 
• 203792-49-8 1-methyl-3-methoxycarbonylpyrazole-3-carboxylic acid chloride 
• 33146-99-5 methyl ester of 1-methylpyrazole-3,5-dicarboxylic acid 
• 117860-57-8 methyl 5-<(benzyloxycarbonyl)amino>-1-methylpyrazole-3-carboxylate 

Downstream Products

• 1193244-87-9 methyl 5-iodo-1-methyl-1H-pyrazole-3-carboxylate 
• 1227409-77-9 1-methyl-5-(quinolin-3-yl)-1H-pyrazol-3-carboxylic acid 
• 1227410-04-9 5-[1-(benzenesulfonyl)-1H-indol-3-yl]-1-methyl-N-[2-(morpholin-4-yl)ethyl]-1H-pyrazole-3-carboxamide 
• 117860-57-8 methyl 5-<(benzyloxycarbonyl)amino>-1-methylpyrazole-3-carboxylate 
• 1021497-95-9 5-[2-(4-bromo-phenylsulfanyl)-acetylamino]-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester 
• 1021497-96-0 1-methyl-5-(2-phenylsulfanyl-acetylamino)-1H-pyrazole-3-carboxylic acid methyl ester 
• 92406-36-5 methyl 3-isopropoxycarbonyl-1,6-dimethyl-4-(3-nitrophenyl)-4,7-dihydropyrazolo[3,4-b]pyridine-5-carboxylate 
• 92406-34-3 methyl 3-methoxycarbonyl-1,6-dimethyl-4-(3-nitrophenyl)-4,7-dihydropyrazolo[3,4-b]pyridine-5-carboxylate 

Relevant articles and documents

COMPOUND HAVING ERK KINASE INHIBITORY ACTIVITY AND USE THEREOF

The invention relates to a compound of formula (I): wherein variables are as defined in the specification. The compound is an inhibitor of an ERK kinase, e.g. ERK1 and/or ERK2 kinase. The invention also relates to the use of the compound and a method for preparing the compound, and a pharmaceutical composition containing the compound.

AMINOPYRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES CONTAINING THE SAME

Provided are aminopyrazole derivatives, a process for the preparation thereof, and a composition for preventing or treating an ischemic disease containing the same. Since the aminopyrazole derivatives of the present invention can reduce an ischemic cell d

4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES

Disclosed are compounds of formula I and II that are bradykinin B1 receptor antagonists and are useful for treating diseases, or relieving adverse symptoms associated with disease conditions, in mammals mediated by bradykinin B1 receptor. Certain of the compounds exhibit increased potency and are also expected to exhibit increased duration of action.