1179062-77-1

Basic information

• Product Name: 4-chloromethyl-1-methoxy-2-(3-methoxypropoxy)-benzene
• Synonyms: 4-chloromethyl-1-methoxy-2-(3-methoxypropoxy)-benzene
• CAS NO: 1179062-77-1
• Molecular Weight: 244.718
• Mol File: 1179062-77-1.mol

Chemical Properties

• CAS DataBase Reference: 4-chloromethyl-1-methoxy-2-(3-methoxypropoxy)-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloromethyl-1-methoxy-2-(3-methoxypropoxy)-benzene(1179062-77-1)
• EPA Substance Registry System: 4-chloromethyl-1-methoxy-2-(3-methoxypropoxy)-benzene(1179062-77-1)

Safety Data

• Hazardous Substances Data: 1179062-77-1(Hazardous Substances Data)

Upstream product

• 621-59-0 isovanillin 
• 172900-74-2 [4-methoxy-3-(3-methoxypropoxy)-phenyl]methanol 

Downstream Products

• 1381757-32-9 C₁₂H₁₇IO₃ 
• 324763-39-5 (R)-2-[4-methoxy-3-(3-methoxypropoxyl)]phenylmethyl-3-methyl-1-chlorobutane 
• 945462-61-3 (R)-methyl 2-(4-methoxy-3-(3-methoxypropoxy)benzyl)-3-methylbutanoate 
• 172900-71-9 (R)-3-[4-methoxy-3-(3-methoxypropoxy)phenyl]-2-(1-methylethyl)propanoic acid 
• 172900-70-8 (R)-2-[4-methoxy-3-(3-methoxypropoxy)benzyl]-3-methylbutanol 
• 172900-72-0 (4R)-3-{(2R)-2-{[4-methoxy-3-(methoxypropoxy)phenyl]methyl-3-methyl}-1-oxobutyl}-4-(phenylmethyl)oxazolidin-2-one 
• 325154-26-5 (2S,7R,E)-2-isopropyl-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-N,N,8-trimethylnon-4-enamide 

Relevant articles and documents

AN IMPROVED PROCESS FOR THE PREPARATION OF ALISKIREN

The present invention relates to an improved process for the preparation of renin inhibitor Aliskiren intermediates of Formula-II and further conversion into Aliskiren and its pharmaceutically acceptable salts.

NOVEL PROCESS FOR THE PREPARATION OF RENIN INHIBITORS

The present invention relates to an improved process for the preparation of compound of Formula-II, which is an intermediate in the preparation of Aliskiren and further conversion of compound of Formula-II into Aliskiren or its pharmaceutically acceptable salts. Formula-II wherein Ri and R2 are independently of one another H, Ci-C6 alkyl, C- C6 halogenalkyl, C]-C6 alkoxy, Ci-C6 alkoxy-Ci-C6 alkyl, or Ci-C6 alkoxy-Ci- C6 alkyloxy and X is halogen selected from fluoro, chloro, bromo and iodo