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CAS

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945462-61-3

(R)-methyl 2-(4-methoxy-3-(3-methoxypropoxy)benzyl)-3-methylbutanoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 945462-61-3 Structure

  • Basic information

    1. Product Name: (R)-methyl 2-(4-methoxy-3-(3-methoxypropoxy)benzyl)-3-methylbutanoate
    2. Synonyms: (R)-methyl 2-(4-methoxy-3-(3-methoxypropoxy)benzyl)-3-methylbutanoate
    3. CAS NO:945462-61-3
    4. Molecular Formula:
    5. Molecular Weight: 324.417
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 945462-61-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-methyl 2-(4-methoxy-3-(3-methoxypropoxy)benzyl)-3-methylbutanoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-methyl 2-(4-methoxy-3-(3-methoxypropoxy)benzyl)-3-methylbutanoate(945462-61-3)
    11. EPA Substance Registry System: (R)-methyl 2-(4-methoxy-3-(3-methoxypropoxy)benzyl)-3-methylbutanoate(945462-61-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 945462-61-3(Hazardous Substances Data)

945462-61-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 945462-61-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,5,4,6 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 945462-61:
(8*9)+(7*4)+(6*5)+(5*4)+(4*6)+(3*2)+(2*6)+(1*1)=193
193 % 10 = 3
So 945462-61-3 is a valid CAS Registry Number.

945462-61-3Downstream Products

945462-61-3Relevant articles and documents

Convergent Synthesis of the Renin Inhibitor Aliskiren Based on C5-C6 Disconnection and CO2H-NH2 Equivalence

Cini, Elena,Banfi, Luca,Barreca, Giuseppe,Carcone, Luca,Malpezzi, Luciana,Manetti, Fabrizio,Marras, Giovanni,Rasparini, Marcello,Riva, Renata,Roseblade, Stephen,Russo, Adele,Taddei, Maurizio,Vitale, Romina,Zanotti-Gerosa, Antonio

, p. 270 - 283 (2016/03/04)

A novel synthesis of the renin inhibitor aliskiren based on an unprecedented disconnection between C5 and C6 was developed, in which the C5 carbon acts as a nucleophile and the amino group is introduced by a Curtius rearrangement, which follows a simultaneous stereocontrolled generation of the C4 and C5 stereogenic centers by an asymmetric hydrogenation. Operational simplicity, step economy, and a good overall yield makes this synthesis amenable to manufacture on scale.

NOVEL PROCESS FOR THE PREPARATION OF RENIN INHIBITORS

-

, (2013/08/28)

The present invention relates to an improved process for the preparation of compound of Formula-II, which is an intermediate in the preparation of Aliskiren and further conversion of compound of Formula-II into Aliskiren or its pharmaceutically acceptable salts. Formula-II wherein Ri and R2 are independently of one another H, Ci-C6 alkyl, C- C6 halogenalkyl, C]-C6 alkoxy, Ci-C6 alkoxy-Ci-C6 alkyl, or Ci-C6 alkoxy-Ci- C6 alkyloxy and X is halogen selected from fluoro, chloro, bromo and iodo

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