117979-53-0Relevant academic research and scientific papers
Precursor-directed combinatorial biosynthesis of cinnamoyl, dihydrocinnamoyl, and benzoyl anthranilates in saccharomyces cerevisiae
Eudes, Aymerick,Benites, Veronica Teixeira,Wang, George,Baidoo, Edward E.K.,Lee, Taek Soon,Keasling, Jay D.,Loqué, Dominique
, (2015/11/24)
Biological synthesis of pharmaceuticals and biochemicals offers an environmentally friendly alternative to conventional chemical synthesis. These alternative methods require the design of metabolic pathways and the identification of enzymes exhibiting ade
Benzoxazole carboxamides for treating CINV and IBS-D
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Page/Page column 6, (2008/06/13)
Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds that exhibit central activity are useful in treating CINV; those that inhibit peripheral receptors are useful to treat IBS-D.
Benzoxazoles as transthyretin amyloid fibril inhibitors: Synthesis, evaluation, and mechanism of action
Razavi, Hossein,Palaninathan, Satheesh K.,Powers, Evan T.,Wiseman, R. Luke,Purkey, Hans E.,Mohamedmohaideen, Nilofar N.,Deechongkit, Songpon,Chiang, Kyle P.,Dendle, Maria T. A.,Sacchettini, James C.,Kelly, Jeffery W.
, p. 2758 - 2761 (2007/10/03)
Benzoxazoles pevent misfolding: Benzoxazole-based inhibitors of transthyretin (TTR) amyloid fibril formation are among the most effective found to date. They stabilize TTR against both acid-mediated misfolding and urea denaturation by raising the activati
Novel synthesis of dianthalexin (Phytoalexin) analogues preparation
Hauteville,Ponchet,Ricci,Favre-Bonvin
, p. 715 - 718 (2007/10/02)
Two phytoalexins, previously isolated from carnation infected by Phytophthora parasitica D., were synthesized: 2-phenyl-7-hydroxy-4H-3,l-benzoxazin-4-one (Dianthalexin) and 2-(2-hydroxybenzoyl)-amino-4-methoxybenzoic acid (Dianthramide A). The first one w
