1180-35-4 Usage
General Description
Acetyl-epipodophyllotoxin is a semi-synthetic derivative of podophyllotoxin, a plant compound with anti-tumor properties. It has been developed as a potential anti-cancer drug and has shown promising results in the treatment of various types of cancer, including lung, breast, and colorectal cancer. Acetyl-epipodophyllotoxin works by inhibiting the growth of cancer cells and inducing apoptosis, or programmed cell death. It also disrupts the formation of microtubules, which are essential for cell division, leading to the suppression of tumor growth. Additionally, it has shown to have lower toxicity and better solubility compared to the natural podophyllotoxin, making it a promising candidate for further development as an anti-cancer agent.
Check Digit Verification of cas no
The CAS Registry Mumber 1180-35-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,8 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1180-35:
(6*1)+(5*1)+(4*8)+(3*0)+(2*3)+(1*5)=54
54 % 10 = 4
So 1180-35-4 is a valid CAS Registry Number.
1180-35-4Relevant articles and documents
Stereoselective synthesis of 4β-acyloxypodophyllotoxin derivatives as insecticidal agents
Che, Zhi-Ping,Tian, Yue-E,Liu, Sheng-Ming,Jiang, Jia,Hu, Mei,Chen, Gen-Qiang
, p. 1028 - 1041 (2018/07/15)
As our ongoing work on research of natural-product-based insecticidal agents, some 4α/β-acyloxypodophyllotoxin derivatives were synthesized, and were evaluated against the pre-third-instar larvae of B. mori, A. dissimilis and M. separate in vivo at the co
