118220-82-9Relevant academic research and scientific papers
Trialkylborane as an Initiator and Terminator of Free Radical Reactions. Facile Routes to Boron Enolates via α-Carbonyl Radicals and Aldol Reaction of Boron Enolates
Nozaki, Kyoko,Oshima, Koichiro,Utimoto, Kiitiro
, p. 403 - 409 (2007/10/02)
A variety of trialkylborane-induced reactions were examined for the preparation of the α-carbonyl radicals: (1) addition of alkyl radical to methyl vinyl ketone, (2) reduction of α-halo ketone, and (3) intramolecular radical addition to α,β-unsaturated carbonyl moiety.Trialkylborane reacted with α-carbonyl radicals to give boron enolates.The resulting boron enolates were efficiently trapped by carbonyl compounds to give β-hydroxy ketones in good yields.
FACILE ROUTES TO BORON ENOLATES. Et3B-MEDIATED REFORMATSKY TYPE REACTION AND THREE COMPONENTS COUPLING REACTION OF ALKYL IODIDES, METHYL VINYL KETONE, AND CARBONYL COMPOUNDS
Nozaki, Kyoko,Oshima, Koichiro,Utimoto, Kiitiro
, p. 1041 - 1044 (2007/10/02)
Reaction of α-bromoketones with Ph3SnH in the presence of Et3B provides boron enolates which react with carbonyl compounds to give β-hydroxyketones in good yields.Et3B-induced Reformatsky type reaction of α-iodoketones with an aldehyde or ketone proceeds without Ph3SnH.
