1182402-81-8

Basic information

• Product Name: 5-Chloro-3-(3-chloropropyl)-3-(2-fluorophenyl)-6-methoxy-1,3-dihydro-2H-indol-2-one
• CAS NO: 1182402-81-8
• Molecular Weight: 368.235
• Mol File: 1182402-81-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Chloro-3-(3-chloropropyl)-3-(2-fluorophenyl)-6-methoxy-1,3-dihydro-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-3-(3-chloropropyl)-3-(2-fluorophenyl)-6-methoxy-1,3-dihydro-2H-indol-2-one(1182402-81-8)
• EPA Substance Registry System: 5-Chloro-3-(3-chloropropyl)-3-(2-fluorophenyl)-6-methoxy-1,3-dihydro-2H-indol-2-one(1182402-81-8)

Safety Data

• Hazardous Substances Data: 1182402-81-8(Hazardous Substances Data)

Upstream product

• 1182402-76-1 methyl (5-chloro-4-methoxy-2-nitrophenyl)(2-fluorophenyl)acetate 
• 84478-76-2 1-chloro-5-fluoro-2-methoxy-4-nitrobenzene 
• 57486-67-6 methyl o-fluorophenylacetate 
• 6940-76-7 1-iodo-3-chloro-propane 
• 1182402-75-0 5-Chloro-3-(2-fluorophenyl)-6-methoxy-1,3-dihydro-2H-indol-2-one 

Downstream Products

• 1182402-80-7 5-Chloro-3-(2-fluorophenyl)-3-[3-(dimethylamino)propyl]-6-methoxy-1,3-dihydro-2H-indol-2-one 
• 1182402-84-1 5-Chloro-3-(2-fluorophenyl)-6-methoxy-3-[3-(4-methylpiperazin-1-yl)propyl]-1,3-dihydro-2H-indol-2-one 

Relevant articles and documents

NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

The present invention relates to novel 3-aminoalkyl-1,3-dihydro-2H-indol-2-one derivatives, to their preparation and to their therapeutic application. The compounds of the present invention correspond to the formula (I): in which the variables are as set forth in the specification. These compounds exhibit a strong affinity and a high selectivity for human arginine-vasopressin (AVP) V1a receptors and some compounds additionally exhibit a strong affinity for AVP V1b receptors.