1182402-92-1

Basic information

• Product Name: 5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-fluorophenyl)-6-methoxy-3-(3-(piperidin-4-yl)propyl)-1,3-dihydro-2H-indol-2-one hydrochloride
• CAS NO: 1182402-92-1
• Molecular Weight: 653.599
• Mol File: 1182402-92-1.mol

Chemical Properties

• CAS DataBase Reference: 5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-fluorophenyl)-6-methoxy-3-(3-(piperidin-4-yl)propyl)-1,3-dihydro-2H-indol-2-one hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-fluorophenyl)-6-methoxy-3-(3-(piperidin-4-yl)propyl)-1,3-dihydro-2H-indol-2-one hydrochloride(1182402-92-1)
• EPA Substance Registry System: 5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-fluorophenyl)-6-methoxy-3-(3-(piperidin-4-yl)propyl)-1,3-dihydro-2H-indol-2-one hydrochloride(1182402-92-1)

Safety Data

• Hazardous Substances Data: 1182402-92-1(Hazardous Substances Data)

Upstream product

• 57486-67-6 methyl o-fluorophenylacetate 
• 84478-76-2 1-chloro-5-fluoro-2-methoxy-4-nitrobenzene 
• 1182402-75-0 5-Chloro-3-(2-fluorophenyl)-6-methoxy-1,3-dihydro-2H-indol-2-one 
• 1188354-96-2 tert-Butyl 4-[3-[5-chloro-3-(2-fluorophenyl)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3-yl]propyl]piperidine-1-carboxylate 
• 1182402-76-1 methyl (5-chloro-4-methoxy-2-nitrophenyl)(2-fluorophenyl)acetate 
• 1182402-94-3 tert-butyl 4-[3-[5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-fluoro-phenyl)-6-methoxy-2-oxo-2,3-dihydro-1H-indol-3-yl]propyl]piperidin-1-carboxylate 

Relevant articles and documents

NOVEL 3-AMINOALKYL-1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

The present invention relates to novel 3-aminoalkyl-1,3-dihydro-2H-indol-2-one derivatives, to their preparation and to their therapeutic application. The compounds of the present invention correspond to the formula (I): in which the variables are as set forth in the specification. These compounds exhibit a strong affinity and a high selectivity for human arginine-vasopressin (AVP) V1a receptors and some compounds additionally exhibit a strong affinity for AVP V1b receptors.