118404-36-7

Upstream product

• 102123-80-8 C₁₉H₂₇NO₆ 
• 102123-81-9 (3-diazo-1-(S)-(2-methylpropyl)-2-oxopropyl)carbamic acid benzyl ester 
• 118252-77-0 (3S)-3-<(benzyloxycarbonyl)amino>-1-bromo-5-methyl-2-oxohexane 
• 2018-66-8 Z-Leu-OH 

Downstream Products

• 118405-12-2 ((S)-4-{(S)-1-[(S)-2-((S)-1-Benzylcarbamoyl-3-methyl-butylcarbamoyl)-1-hydroxy-ethyl]-3-methyl-butylcarbamoyl}-1-isobutyl-2-oxo-5-phenyl-pentyl)-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Renin inhibitors containing isosteric replacements of the amide bond connecting the P3 and P2 sites

Renin inhibitors having 13 different isosteres connecting the P3 and P2 positions have been prepared. Synthetic routes and in vitro activity exhibited by these compounds are discussed. The two most potent compounds, 47 and 48, contai

Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements

Inhibitors of aminopeptidase enzymes have been prepared by the synthesis of peptide substrate analogues in which the scissile amide bond has been replaced with the hydrolytically stable ketomethylene (-COCH2-) and hydroxyethylene [-CH(OH)CHsub