118460-13-2Relevant academic research and scientific papers
Racemization-Free Synthesis of Morpholinone Derivatives from α-Amino Acids
Samanta, Sauvik,Mal, Abhijit,Halder, Sandipan,Ghorai, Manas K.
, p. 3776 - 3782 (2015/11/28)
A simple strategy is reported for the synthesis of chiral N-protected morpholinone derivatives by a base (potassium carbonate)-mediated cyclization reaction of N-protected α-amino acids with 1,2-dibromoethane. The morpholinone derivatives are obtained in
Simple and efficient one pot synthetic protocol to construct morpholin-2-ones
Yellol, Gorakh S.,Mohapatra, Debendra K.,Gurjar, Mukund K.,Sun, Chung-Ming
experimental part, p. 431 - 439 (2011/05/02)
A new one pot synthetic method to construct 3-substituted morpholine-2-one derivatives is presented. Amino acids refluxed with 1,2-dibromoethane and potassium carbonate in acetonitrile followed by treatment with benzyl bromide in same pot furnished the 3-
