1184918-34-0

Basic information

• Product Name: tert-Butyl 3-aMino-4-(hydroxyMethyl)pyrrolidine-1-carboxylate
• Synonyms: tert-Butyl 3-aMino-4-(hydroxyMethyl)pyrrolidine-1-carboxylate;Cis-1-N-Boc-3-amino-4-(hydroxymethyl)pyrrolidine;1-Boc-3-amino-4-(hydroxymethyl)pyrrolidine;1-Pyrrolidinecarboxylic acid, 3-amino-4-(hydroxymethyl)-, 1,1-dimethylethyl ester
• CAS NO: 1184918-34-0
• Molecular Formula: C10H20N2O3
• Molecular Weight: 216.2774
• Mol File: 1184918-34-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-Butyl 3-aMino-4-(hydroxyMethyl)pyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 3-aMino-4-(hydroxyMethyl)pyrrolidine-1-carboxylate(1184918-34-0)
• EPA Substance Registry System: tert-Butyl 3-aMino-4-(hydroxyMethyl)pyrrolidine-1-carboxylate(1184918-34-0)

Safety Data

• Hazardous Substances Data: 1184918-34-0(Hazardous Substances Data)

Upstream product

• 251948-87-5 (allyl-tert-butoxycarbonyl-amino)-acetic acid ethyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 251948-88-6 N-allyl-N-(tert-butyloxycarbonyl)-glycinal 
• 31954-27-5 N-(tert-butoxycarbonyl)glycine methyl ester 
• 116613-80-0 N-allyl-N-(tert-butoxycarbonyl)glycine methyl ester 
• 623582-43-4 1-(2-hydroxy-1-phenyl-ethyl)-tetrahydro-pyrrolo[3,4-c]isoxazole-5-carboxylic acid tert-butyl ester 

Downstream Products

• 369623-85-8 (3R,4R)-4-Amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 

Relevant articles and documents

TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS

The present invention relates to compounds that are inhibitors of hepatitis B virus (HBV). Compounds of this invention are useful alone or in combination with other agents for treating, ameliorating, preventing or curing HBV infection and related conditions. The present invention also relates to pharmaceutical compositions containing said compounds.

Synthesis of Cyclic and Acyclic β-Amino Acids via Chelation-Controlled 1,3-Dipolar Cycloaddition

Isoxazolidines have been synthesized in diastereomeric excess up to 94% via a MgBr2-induced chelation-controlled 1,3-dipolar cycloaddition reaction with N-hydroxyphenylglycinol as a chiral auxiliary. The diastereomerically pure isoxazolidines were further transformed into cyclic and acyclic β-amino acid derivatives.