251948-87-5

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 2-(allyl(tert-butoxycarbonyl)aMino)acetate is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure allows for the creation of complex molecules that can be used in the treatment of different medical conditions.
Used in Agrochemical Industry:
In the agrochemical industry, ethyl 2-(allyl(tert-butoxycarbonyl)aMino)acetate serves as a key intermediate in the synthesis of various agrochemicals. Its properties make it suitable for the development of compounds that can be used in crop protection and other agricultural applications.
Used as a Reagent in Chemical Reactions:
Ethyl 2-(allyl(tert-butoxycarbonyl)aMino)acetate is also utilized as a reagent in various chemical reactions. Its ability to participate in a range of reactions makes it a valuable tool for chemists working on the synthesis of new compounds.
Used in the Development of New Materials:
ethyl 2-(allyl(tert-butoxycarbonyl)aMino)acetate has potential applications in the development of new materials. Its unique structure and properties can contribute to the creation of innovative materials with specific characteristics for various industries.
Used in the Synthesis of Bioactive Compounds:
Ethyl 2-(allyl(tert-butoxycarbonyl)aMino)acetate is used as a building block for the synthesis of bioactive compounds. Its presence in these compounds can lead to the development of new drugs and other bioactive substances with potential therapeutic applications.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 105-36-2 ethyl bromoacetate 
• 107-11-9 1-amino-2-propene 
• 14719-37-0 ethyl 2-(tert-butoxycarbonylamino)acetate 
• 106-95-6 allyl bromide 
• 3182-79-4 N-allylglycine ethyl ester 

Downstream Products

• 1246016-70-5 ethyl 2-(tert-butoxycarbonyl(5-(2,4-difluorophenyl)-2-(ethoxycarbonothioylthio)-5-oxopentyl)amino)acetate 
• 1184918-34-0 tert-butyl cis-3-amino-4-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 1463484-37-8 tert-butyl N-allyl-N-(2-isothiazol-5-yl-2-oxo-ethyl)carbamate 
• 1429646-79-6 tert-butyl N-allyl-N-[2-(methoxy(methyl)amino)-2-oxo-ethyl]carbamate 
• 251948-88-6 N-allyl-N-(tert-butyloxycarbonyl)-glycinal 

Relevant academic research and scientific papers

A versatile polypeptoid platform based on N-allyl glycine

N-Allyl glycine N-carboxyanhydride (NCA) was synthesized and polymerized by ring opening polymerization under homo- or heterophase conditions to afford well-defined polypeptoids (MW = 1.5-10.5 kg mol-1, PDI = 1.1-1.4). Poly(N-allyl glycine) demonstrated stimuli-responsive behaviour in water and was readily modified via thiol-ene photochemistry under experimentally benign conditions. This journal is

Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor

The beta-site APP cleaving enzyme 1, known as BACE1, has been a widely pursued Alzheimer's disease drug target owing to its critical role in the production of amyloid-beta. We have previously reported the clinical development of LY2811376 and LY2886721. L

TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS

The present invention relates to compounds that are inhibitors of hepatitis B virus (HBV). Compounds of this invention are useful alone or in combination with other agents for treating, ameliorating, preventing or curing HBV infection and related conditions. The present invention also relates to pharmaceutical compositions containing said compounds.

BACE INHIBITORS

The present invention provides compounds of Formula I useful as BACE inhibitors in the treatment of e.g. Alzheimer's disease : wherein A is selected from the group consisting of; of; R1 is H or F; R2 is H, -OCH3, C1-C3 alkyl,; R3 is H, -CH3, or -OCH3; and R4 is H or F; or a pharmaceutically acceptable salt thereof.

Easy and efficient generation of reactive anions with free and supported ylides as neutral Bronsted bases

The tris(dimethylamino)-C-dimethylphosphorus ylide 5 and the tris(dimethylamino)phosphorus ylide C-bound to Merrifield's resin 6 are used as strong non-nucleophilic bases in N-alkylation reactions of β-amino phosphine oxides and α-amino acid derivatives,

Pd-catalyzed asymmetric allylic alkylation of 3-acetoxy-N-(tert- butyloxycarbonyl)-1,2,3,6-tetrahydropyridine - Preparation of key intermediates for natural product synthesis

A convenient synthesis of racemic tetrahydropyridine 1 was developed. Pd-catalyzed allylic alkylation of 1 with malonate and dimethylacetoxymalonate as nucleophiles with the phosphanylcarboxylic acid L1 and the dihydrooxazol L2 as ligands, were carried out and gave enantiomeric excesses of up to 98%. Absolute configurations were determined for all compounds described. From the alkylation products (+)- and (-)-2a, and (+)- and (-)-2b a variety of versatile, nonracemic chiral intermediates were prepared.