1185503-48-3 Usage
General Description
The chemical compound "Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3R)-" is a complex organic compound that belongs to the morpholine class of chemicals. It is composed of a morpholine ring, a trifluoromethylphenyl group, and a fluoro phenyl group. Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3R)- has a specific stereochemistry, with two stereocenters denoted as (2S,3R). Morpholine derivatives are widely used in various industrial applications, including as a solvent, corrosion inhibitor, and chemical intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. The specific structure of "Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3R)-" makes it valuable in organic synthesis and chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 1185503-48-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,5,5,0 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1185503-48:
(9*1)+(8*1)+(7*8)+(6*5)+(5*5)+(4*0)+(3*3)+(2*4)+(1*8)=153
153 % 10 = 3
So 1185503-48-3 is a valid CAS Registry Number.
1185503-48-3Relevant articles and documents
Synthesis of the major isomers of Aprepitant and Fosaprepitant
Wan, Wei-Li,He, Yun,Guan, Mei,Li, Xiao-Long,Cheng, Xu,Wu, Yong
, p. 1118 - 1122 (2014/01/06)
The synthesis of two isomers of Aprepitant (APT) and three isomers of Fosaprepitant (FPT), crucial components for quality control in manufacturing, is described. Herein, three chiral centers in the isomers of Aprepitant are established in high yield by in
PREPARATION OF MORPHOLINE DERIVATIVES
-
, (2009/10/21)
This invention relates to processes and intermediates for the stereoselective morpholine derivatives. The invention in particular allows the stereoselective preparation of the drugs aprepitant and fosaprepitant.
