118555-06-9Relevant academic research and scientific papers
SYNTHESIS OF PHENOXYPYRIDINES UNDER PHASE TRANSFER CATALYSIS CONDITIONS
Abele, E. M.,Gol'dberg, Yu. Sh.,Gavars, M. P.,Gaukhman, A. P.,Shimanskaya, M. V.
, p. 290 - 294 (1988)
Reactions of halopyridines with alkali metal phenoxides in a two phase liquid-solid catalytic system, rather than in a liquid-liquid phase transfer catalytic system, make it possible to prepare 2-, 3-, and 4-phenoxypyridines from unactivated bromo- or chloropyridines and 2-chloropicolines.In polyhalogenated pyridines only α- and γ-halogen atoms undergo substitution. 7,8-Dibromo-6-azaphenoxane has been prepared by the reaction of 2,3,5,6-tetrabromopyridine with the dipotassium salt of pyrocatechol.
