118653-92-2

Upstream product

• 113898-52-5 (2S,3S)-dimethyl 2-(benzyloxy)-3-hydroxysuccinate 
• 98-59-9 p-toluenesulfonyl chloride 
• 104333-70-2 (2R,3R)-2-benzyloxy-3-hydroxy-1,4-butanedioic acid dimethyl ester 
• 38270-72-3 dimethyl 2,3-O-benzylidene-L-tartrate 
• 91326-83-9 (4S,5S)-dimethyl 2-phenyl-1,3-dioxolane-4,5-dicarboxylate 

Downstream Products

• 118653-93-3 (2R,3R)-2-Benzyloxy-3-p-tolylsulfonyloxybutane-1,4-diol 
• 118653-93-3 (2S,3S)-2-Benzyloxy-3-p-tolylsulfonyloxybutane-1,4-diol 
• 118653-95-5 (2S,3S)-1-Chloro-2-benzyloxy-4-p-tolylsulfonyloxybutane-2-ol 
• 118653-94-4 (3R,2S)-2-Benzyloxy-3,4-epoxybutyl p-toluenesulfonate 
• 118653-91-1 (3R,2S)-2-Benzyloxy-3,4-epoxybutan-1-ol 
• 118653-95-5 (2R,3R)-1-Chloro-3-benzyloxy-4-p-tolylsulfonyloxybutane-2-ol 
• 118653-94-4 (3S,2R)-2-Benzyloxy-3,4-epoxybutyl p-toluenesulfonate 
• 195512-73-3 (3S,2R)-2-Benzyloxy-3,4-epoxybutan-1-ol 

Relevant academic research and scientific papers

(2S,3R)-2-Benzyloxy-3,4-epoxybutan-1-ol; A Versatile Synthetic Building Block Formally Derived From (u)-Tartaric acid

The title chiral C4-building block 1, a meso-tartaric acid synthon, is prepared from dimethyl (R,R)-O,O'-benzylidenetartrate on a multigram scale.The key step is a tosylation-reduction sequence which leads to the diol 5.