(2S,3R)-2-Benzyloxy-3,4-epoxybutan-1-ol; A Versatile Synthetic Building Block Formally Derived From (u)-Tartaric acid

DOI: 10.1055/s-1988-27577

Source and publish data:

Synthesis p. 373 - 375 (1988)

Update date:2022-08-02

Topics:

Authors:

Adam, Geo

Seebach, Dieter

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Article abstract of DOI:10.1055/s-1988-27577

The title chiral C4-building block 1, a meso-tartaric acid synthon, is prepared from dimethyl (R,R)-O,O'-benzylidenetartrate on a multigram scale.The key step is a tosylation-reduction sequence which leads to the diol 5.

Full text of DOI:10.1055/s-1988-27577

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