1187-13-9

Basic information

• Product Name: 2-Ethylcrotonic acid
• Synonyms: 2-Ethylcrotonic acid;2-Butenoic acid, 2-ethyl-, (E)-
• CAS NO: 1187-13-9
• Molecular Formula: C₆H₁₀O₂
• Molecular Weight: 114.1424
• Mol File: 1187-13-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 45.5°C
• Boiling Point: 209.05°C
• Flash Point: 113.9 °C
• Appearance: /
• Density: 0.9578
• Refractive Index: 1.4475
• CAS DataBase Reference: 2-Ethylcrotonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ethylcrotonic acid(1187-13-9)
• EPA Substance Registry System: 2-Ethylcrotonic acid(1187-13-9)

Safety Data

• Hazardous Substances Data: 1187-13-9(Hazardous Substances Data)

Usage

General Description

2-Ethylcrotonic acid, also known as 2-Ethyl-2-methylacrylic acid, is a chemical compound with the formula C6H10O2. It is a colorless liquid with a strong, pungent odor. 2-Ethylcrotonic acid is commonly used as a chemical intermediate in the production of pharmaceuticals and agricultural chemicals. It is also used in the manufacture of plastics, coatings, and adhesives. Additionally, it is utilized as a cross-linking agent in the production of water-based polymers. The compound is hazardous if ingested or inhaled, and exposure can cause irritation to the respiratory system, skin, and eyes. Proper precautions and safety measures should be taken when handling 2-Ethylcrotonic acid.

Upstream product

• 3639-21-2 2-ethyl-2-hydroxybutyric acid 
• 5465-11-2 ethyl 2-ethyl-3-hydroxybutanoate 
• 88-09-5 2-Ethylbutanoic acid 
• 99115-00-1 ethyl 2-ethylbut-2-enoate 
• 42549-97-3 (E)-2-Ethyl-but-2-enoic acid methyl ester 
• 77-65-6 carbromal 
• 4411-91-0 2-ethyl-crotonic acid amide 
• 80-58-0 2-Bromobutyric acid 
• 75-07-0 acetaldehyde 
• 108-24-7 acetic anhydride 
• 601-75-2 ethylmalonic acid 
• 123-63-7 paracetaldehyde 
• 5582-86-5 2-ethyl-2-hydroxy-butyric acid ethyl ester 
• 1114-37-0 3-ethylpent-3-en-2-one 

Downstream Products

• 100121-65-1 2-ethyl-trans-crotonic acid phenyl ester 
• 64-19-7 acetic acid 
• 107-92-6 butyric acid 
• 627-20-3 (Z)-pent-2-ene 

Relevant articles and documents

Ligand-controlled divergent dehydrogenative reactions of carboxylic acids via C–H activation

Dehydrogenative transformations of alkyl chains to alkenes through methylene carbon-hydrogen (C–H) activation remain a substantial challenge. We report two classes of pyridine-pyridone ligands that enable divergent dehydrogenation reactions through palladium-catalyzed b-methylene C–H activation of carboxylic acids, leading to the direct syntheses of a,b-unsaturated carboxylic acids or g-alkylidene butenolides. The directed nature of this pair of reactions allows chemoselective dehydrogenation of carboxylic acids in the presence of other enolizable functionalities such as ketones, providing chemoselectivity that is not possible by means of existing carbonyl desaturation protocols. Product inhibition is overcome through ligand-promoted preferential activation of C(sp3)–H bonds rather than C(sp2)–H bonds or a sequence of dehydrogenation and vinyl C–H alkynylation. The dehydrogenation reaction is compatible with molecular oxygen as the terminal oxidant.

γ-C (sp3)-H bond functionalisation of α,β-unsaturated amides through an umpolung strategy

The nucleophilic γ-phenylation and γ-alkylation of α,β-unsaturated amides have been developed. This umpolung reaction allows the regioselective introduction of phenyl and alkyl groups to a vinylketene N,O-acetal, which is generated in situ from an α,β-uns