1187-84-4Relevant articles and documents
Ostermayer,Tarbell
, p. 3752,3754 (1960)
Asymmetric synthesis of (S,R)- and (R,R)-methiin stereoisomers
Kolodiazhna, Anastasy О.,Skliarov, Аleksei I.,Slastennikova, Alena A.,Kolodiazhnyi, Oleg I.
, p. 713 - 717 (2020)
An asymmetric synthesis of (+)- and (–)-methiine (S-methyl-(R)-cysteine sulfoxide) diastereomers has been developed. These natural sulfur compounds were isolated from a variety of Brassica vegetables. As the starting compound, (R)-cysteine was used, which was methylated to form (R)-S-methylcysteine. Then the oxidation of S-methylcysteine with tert-butyl hydroperoxide catalyzed by the chiral tetra(isopropylate)titanium/(S)- or (R)-Binol complex led to the formation of (1 R,2S)-(+)- or (1 R,2R)-(–)-methiin stereomers.
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Frankel,M.
, p. 1390 - 1393 (1960)
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Direct monitoring of biocatalytic deacetylation of amino acid substrates by1H NMR reveals fine details of substrate specificity
De Cesare, Silvia,McKenna, Catherine A.,Mulholland, Nicholas,Murray, Lorna,Bella, Juraj,Campopiano, Dominic J.
supporting information, p. 4904 - 4909 (2021/06/16)
Amino acids are key synthetic building blocks that can be prepared in an enantiopure form by biocatalytic methods. We show that thel-selective ornithine deacetylase ArgE catalyses hydrolysis of a wide-range ofN-acyl-amino acid substrates. This activity was revealed by1H NMR spectroscopy that monitored the appearance of the well resolved signal of the acetate product. Furthermore, the assay was used to probe the subtle structural selectivity of the biocatalyst using a substrate that could adopt different rotameric conformations.
Composition for promoting differentiation of skin keratinocyte comprising a SAC derivatives or a SMC derivatives
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Paragraph 0057-0060; 0062-0064; 0111-0114; 0116-0118; 0161, (2021/02/02)
The present invention relates to a composition for promoting keratinocyte differentiation. More specifically, SAC derivative or SMC derivatives as an active ingredient promotes differentiation of keratinocytes to promote skin keratinocyte differentiation, has excellent anti-wrinkling effect, skin barrier recovery effect, and is applicable to pharmaceutical, cosmetic, soap, body, shampoo and pack.