1187344-41-7

Upstream product

• 121086-26-8 1-benzyloxy-2-methoxy-4-methyl-5-nitrobenzene 
• 78136-55-7 1-(benzyloxy)-2-methoxy-4-methylbenzene 
• 1258423-42-5 N₁-(2,5-dichloropyrimidin-4-yl)-4-methoxybenzene-1,2-diamine 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1258423-50-5 N-(cyanomethyl)-N-(2-(2,5-dichloropyrimidin-4-ylamino)-5-methoxyphenyl)methanesulfonamide 
• 1187343-47-0 N-(2-(5-chloro-2-(3,4,5-trimethoxyphenylamino)pyrimidin-4-ylamino)-5-methoxyphenyl)methanesulfonamide 
• 1258492-33-9 N-(2-(5-chloro-2-(4,6-dimethoxypyridin-3-ylamino)pyrimidin-4-ylamino)-5-methoxyphenyl)methanesulfonamide 

Relevant academic research and scientific papers

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

FLUORO SUBSTITUTED PYRIMIDINE COMPOUNDS AS JAK3 INHIBITORS

The invention relates to compounds of formula (I) wherein AA, R2 to R7 and X1 to X3 have the meaning as cited in the description and the claims. Said compounds are useful as selective inhibitors of JAK3 over JAK

ORTHO SUBSTITUTED PYRIMIDINE COMPOUNDS AS JAK INHIBITORS

The invention relates to compounds of formula (I) wherein X1 to X3, R, R2 to R7 and AA have the meaning as cited in the description and the claims. Said compounds are useful as JAK inhibitors for the treatment o

ORTHO SUBSTITUTED PYRIMIDINE COMPOUNDS AS JAK INHIBITORS

The present invention relates to compounds of formula (I), wherein X1 to X3, R, R2 to R7 and AA have the meaning as cited in the description and the claims. Said compounds are useful as JAK inhibitors for the tr

SULFONAMIDES AND SULFAMIDES AS ZAP-70 INHIBITORS

The invention relates to compounds of formula (I), wherein R1 to R6 and T0 have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of ZAP-70 for the treatment or prophylaxis of

HETEROCYCLYLAMINOPYRIMIDINES AS KINASE INHIBITORS

The invention relates to compounds of formula (I), wherein R1 to R6 and T0 have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of ZAP-70, Syk or JAK3 for the treatment or pr

SULFONAMIDES AS ZAP-70 INHIBITORS

The invention relates to compounds of formula (I), wherein R1 to R9 and R4a have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of ZAP-70 for the treatment or prophylaxis of