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118743-81-0

(ALPHAR)-N-HYDROXY-ALPHA-METHYL-BENZENEMETHANAMINE ETHANEDIOATE SALT, also known as rasagiline mesylate, is a medication primarily used for the treatment of Parkinson's disease. It functions as a selective, irreversible monoamine oxidase-B (MAO-B) inhibitor, which increases dopamine levels in the brain, thereby improving motor symptoms and reducing "off" time in patients. Rasagiline mesylate is typically administered orally and is well-absorbed by the body. It is also being investigated for its potential neuroprotective and disease-modifying effects, with common side effects including headache, joint pain, nausea, and insomnia.

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  • 118743-81-0 Structure

  • Basic information

    1. Product Name: (ALPHAR)-N-HYDROXY-ALPHA-METHYL-BENZENEMETHANAMINE ETHANEDIOATE SALT
    2. Synonyms: (ALPHAR)-N-HYDROXY-ALPHA-METHYL-BENZENEMETHANAMINE ETHANEDIOATE SALT;(R)-N-(α-Methylbenzyl)hydroxylaMine oxalate salt;N-[(1R)-1-Phenylethyl]hydroxylamine oxalate salt;N-[(1R)-1-Phenylethyl]hydroxylamine: oxalic acid;N-[(1R)-1-Phenylethyl]hydroxylamine
    3. CAS NO:118743-81-0
    4. Molecular Formula: C2H2O4*C8H11NO
    5. Molecular Weight: 227.22
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 118743-81-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (ALPHAR)-N-HYDROXY-ALPHA-METHYL-BENZENEMETHANAMINE ETHANEDIOATE SALT(CAS DataBase Reference)
    10. NIST Chemistry Reference: (ALPHAR)-N-HYDROXY-ALPHA-METHYL-BENZENEMETHANAMINE ETHANEDIOATE SALT(118743-81-0)
    11. EPA Substance Registry System: (ALPHAR)-N-HYDROXY-ALPHA-METHYL-BENZENEMETHANAMINE ETHANEDIOATE SALT(118743-81-0)

  • Safety Data

    1. Hazard Codes: C
    2. Statements: 22-34
    3. Safety Statements: 26-36/37/39-45
    4. RIDADR: UN 3261 8 / PGIII
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 118743-81-0(Hazardous Substances Data)

118743-81-0 Usage

Uses

Used in Pharmaceutical Industry:
(ALPHAR)-N-HYDROXY-ALPHA-METHYL-BENZENEMETHANAMINE ETHANEDIOATE SALT is used as a medication for the treatment of Parkinson's disease. It is utilized as a selective, irreversible monoamine oxidase-B (MAO-B) inhibitor to increase dopamine levels in the brain, improving motor symptoms and reducing "off" time in patients.
Used in Neuroprotective Research:
(ALPHAR)-N-HYDROXY-ALPHA-METHYL-BENZENEMETHANAMINE ETHANEDIOATE SALT is used as a subject of research for its potential neuroprotective and disease-modifying effects in the context of Parkinson's disease. This involves studying its ability to protect neurons from degeneration and potentially slow the progression of the disease.

Check Digit Verification of cas no

The CAS Registry Mumber 118743-81-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,7,4 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 118743-81:
(8*1)+(7*1)+(6*8)+(5*7)+(4*4)+(3*3)+(2*8)+(1*1)=140
140 % 10 = 0
So 118743-81-0 is a valid CAS Registry Number.

118743-81-0 Well-known Company Product Price

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  • Aldrich

  • (690236)  (R)-N-(α-Methylbenzyl)hydroxylamineoxalatesalt  ≥96%

  • 118743-81-0

  • 690236-1G

  • 1,663.74CNY

  • Detail

  • Aldrich

  • (690236)  (R)-N-(α-Methylbenzyl)hydroxylamineoxalatesalt  ≥96%

  • 118743-81-0

  • 690236-5G

  • 5,857.02CNY

  • Detail

118743-81-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name oxalic acid,N-[(1R)-1-phenylethyl]hydroxylamine

1.2 Other means of identification

Product number -
Other names [(1R)-1-(hydroxyammonio)ethyl]benzene oxalate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:118743-81-0 SDS

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