195196-15-7

Basic information

• Product Name: (3S,4S)-4-hydroxy-3-phenyl-N-(1-phenylethyl)isoxazolidinone
• Synonyms: (3S,4S)-4-hydroxy-3-phenyl-N-(1-phenylethyl)isoxazolidinone
• CAS NO: 195196-15-7
• Molecular Weight: 283.327
• Mol File: 195196-15-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,4S)-4-hydroxy-3-phenyl-N-(1-phenylethyl)isoxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4S)-4-hydroxy-3-phenyl-N-(1-phenylethyl)isoxazolidinone(195196-15-7)
• EPA Substance Registry System: (3S,4S)-4-hydroxy-3-phenyl-N-(1-phenylethyl)isoxazolidinone(195196-15-7)

Safety Data

• Hazardous Substances Data: 195196-15-7(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 127001-34-7 N-Benzylidene<(R)-(-)-α-methylbenzyl>amine N-oxide 
• 118743-81-0 (R)-(+)-α-methylbenzylhydroxylamine oxalate 
• 195196-19-1 C₄₁H₆₁NO₄Si₂ 

Downstream Products

• 158830-39-8 methyl (2S,3S)-2-hydroxy-3-(N-tert-butoxycarbonylamino)-3-phenylpropanoate 
• 144541-45-7 methyl (2S,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 
• 7309-55-9 (2S,3S)-N-benzoyl-3-phenylisoserine 
• 7309-53-7 threo-3-phenylisoserine 
• 59937-41-6 (2S,3S)-3-tert-Butoxycarbonylamino-2-hydroxy-3-phenyl-propionic acid 

Relevant articles and documents

Totally stereocontrolled nitrone-ketene acetal based synthesis of (2S,3S)-N-benzoyl-and N-boc-phenylisoserine

A novel, nitrone-ketene acetal based approach to enantiopure (2S,3S)-N- benzoyl- and N-boc-phenylisoserine has been realized. The convergent approach, which involves the intermediacy of isoxazolidinones, proceeds in up to 59% overall yield and requires only three operations from the starting nitrones.