118744-89-1Relevant academic research and scientific papers
Stereoselective synthesis of 3'-C-methylene- and 2'-methyl-3'-C-methylene-3'-deoxythymidine
Riehokainen, Elena,Mikerin, Igor E.,Slobodyan, Nickolai N.,Tulebaev, Marat B.,Severin, Sergey E.
, p. 161 - 166 (2007/10/03)
Stereoselective synthesis of 3'-C-methylene- and 2'-methyl-3'-C-methylene-3'-deoxythymidine is described, the key reaction being the formation of 3-C-methylene function by catalytic isomerization of a chiral epoxyalcohol, prepared from commercially availa
3'-C-branched 2'-deoxy-5-methyluridines: Synthesis, enzyme inhibition, and antiviral properties
Fedorov,Kazmina,Novicov,Gurskaya,Bochkarev,Jasko,Victorova,Kukhanova,Balzarini,De Clercq,Krayevsky
, p. 4567 - 4575 (2007/10/02)
A synthesis scheme for 3'-C-methyl-2'-deoxynucleosides and 3'-C- methylidene-2',3'-dideoxy-5-methyluridine has been proposed with 2- deoxyribose as the starting material. Methyl 5-O-benzoyl-2-deoxyribofuranose was oxidized and the mixture of the 3'-keto d
SYNTHESIS OF 2',3'-DIDEOXY-3'-METHYLENE PYRIMIDINE NUCLEOSIDES AS POTENTIAL ANTI-AIDS AGENTS
Sharma, M.,Bobek, M.
, p. 5839 - 5842 (2007/10/02)
Efficient synthesis of 2',3'-dideoxy-3'-methylene nucleoside analogs starting from 2'-deoxy-3'-keto-nucleosides is described.
