144072-00-4Relevant articles and documents
3'-C-branched 2'-deoxy-5-methyluridines: Synthesis, enzyme inhibition, and antiviral properties
Fedorov,Kazmina,Novicov,Gurskaya,Bochkarev,Jasko,Victorova,Kukhanova,Balzarini,De Clercq,Krayevsky
, p. 4567 - 4575 (1992)
A synthesis scheme for 3'-C-methyl-2'-deoxynucleosides and 3'-C- methylidene-2',3'-dideoxy-5-methyluridine has been proposed with 2- deoxyribose as the starting material. Methyl 5-O-benzoyl-2-deoxyribofuranose was oxidized and the mixture of the 3'-keto d
3'-C-Phosphonates as Nucleotides Analogues Synthesis Starting from Original C-Phosphonosugars (in ribo- and deoxyribo- series)
Serra, Corine,Dewynter, Georges,Montero, Jean-Louis,Imbach, Jean-Louis
, p. 8427 - 8444 (2007/10/02)
3-C-phosphonosugars were synthetised starting from 2-deoxy-D-ribose and α-D-xylofuranose via the Pudovic rection followed by reduction.Their condensation with nucleobases (thymine and adenine) gave original 3'-C-phosphononucleosides in ribo- and 2-deoxyribo- series, with a stereocontrol of the reactions.Key words: 3-C-phosphonosugar, 3'-C-phosphononucleoside, Pudovic reaction, α-hydroxyphosphonate