144071-99-8Relevant academic research and scientific papers
2′,3′-dideoxy- and 3′-azido-2′,3′-dideoxynucleosides of 5-phenyl-2(1H)-pyrimidinone. Preparation of 2′,3′-dideoxypentofuranoses
Krecmerova, Marcela,Hrebabecky, Hubert,Masojidkova, Milena,Holy, Antonin
, p. 478 - 488 (2007/10/03)
The synthesis of methyl 3-azido-5-benzoyl-2,3-dideoxy-β-D-ribofuranoside (10) from methyl 2-deoxy-D-ribofuranoside (1) and its use for the preparation of 3′-azido-2′,3′-dideoxy-β-D-ribofuranosides is described. Reaction of methylglucoside 1 with benzoyl c
3'-C-Phosphonates as Nucleotides Analogues Synthesis Starting from Original C-Phosphonosugars (in ribo- and deoxyribo- series)
Serra, Corine,Dewynter, Georges,Montero, Jean-Louis,Imbach, Jean-Louis
, p. 8427 - 8444 (2007/10/02)
3-C-phosphonosugars were synthetised starting from 2-deoxy-D-ribose and α-D-xylofuranose via the Pudovic rection followed by reduction.Their condensation with nucleobases (thymine and adenine) gave original 3'-C-phosphononucleosides in ribo- and 2-deoxyribo- series, with a stereocontrol of the reactions.Key words: 3-C-phosphonosugar, 3'-C-phosphononucleoside, Pudovic reaction, α-hydroxyphosphonate
3'-C-branched 2'-deoxy-5-methyluridines: Synthesis, enzyme inhibition, and antiviral properties
Fedorov,Kazmina,Novicov,Gurskaya,Bochkarev,Jasko,Victorova,Kukhanova,Balzarini,De Clercq,Krayevsky
, p. 4567 - 4575 (2007/10/02)
A synthesis scheme for 3'-C-methyl-2'-deoxynucleosides and 3'-C- methylidene-2',3'-dideoxy-5-methyluridine has been proposed with 2- deoxyribose as the starting material. Methyl 5-O-benzoyl-2-deoxyribofuranose was oxidized and the mixture of the 3'-keto d
