1187732-65-5 Usage
General Description
6-Chloro-2-fluoro-3-iodopyridine is a chemical compound that is supplied at a concentration of 95%. It is a heterocyclic organic compound with a pyridine ring that contains chlorine, fluorine, and iodine atoms. 6-Chloro-2-fluoro-3-iodopyridine, 95% is commonly used as a building block in organic synthesis, particularly in the pharmaceutical industry for the production of various drugs and chemical intermediates. Its unique structure and reactivity make it a valuable reagent for the introduction of specific functional groups into molecular structures. This chemical is often utilized as a key component in the development of new pharmaceuticals and research chemicals due to its versatile properties and potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1187732-65-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,7,7,3 and 2 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1187732-65:
(9*1)+(8*1)+(7*8)+(6*7)+(5*7)+(4*3)+(3*2)+(2*6)+(1*5)=185
185 % 10 = 5
So 1187732-65-5 is a valid CAS Registry Number.
1187732-65-5Relevant articles and documents
Continuous Flow Preparation of (Hetero)benzylic Lithiums via Iodine-Lithium Exchange Reaction under Barbier Conditions
Weidmann, Niels,Harenberg, Johannes H.,Knochel, Paul
supporting information, p. 5895 - 5899 (2020/08/12)
Herein we report the generation of benzylic lithiums via an iodine-lithium exchange reaction on benzylic iodides performed in continuous flow using tBuLi as the exchange reagent. The resulting benzylic lithium species are trapped in situ by carbonyl electrophiles under Barbier conditions, resulting in benzylic secondary and tertiary alcohols. This flow procedure further allows the generation of highly reactive heterobenzylic lithium compounds, which are difficult to generate under batch conditions. A general scale-up was possible without further optimization.
