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40851-92-1

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40851-92-1 Usage

General Description

5-CHLORO-2-METHYL-3H-IMIDAZO[4,5-B]PYRIDINE is a chemical compound with the molecular formula C8H6ClN3. It is a heterocyclic aromatic compound that contains both imidazole and pyridine rings. 5-CHLORO-2-METHYL-3H-IMIDAZO[4,5-B]PYRIDINE is used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceuticals. It has been identified as a potential antiviral and antimicrobial agent, and research is ongoing to explore its potential therapeutic applications. Additionally, it is also used as a reagent in organic synthesis for the preparation of various other chemical compounds. Safety precautions should be taken when handling this chemical, as it may pose health and environmental risks.

Check Digit Verification of cas no

The CAS Registry Mumber 40851-92-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,8,5 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 40851-92:
(7*4)+(6*0)+(5*8)+(4*5)+(3*1)+(2*9)+(1*2)=111
111 % 10 = 1
So 40851-92-1 is a valid CAS Registry Number.

40851-92-1Relevant articles and documents

Access to 2-pyridinylamide and imidazopyridine from 2-fluoropyridine and amidine hydrochloride

Chen, Lu,Huang, Shuo,Ji, Xiaoliang,Li, Jiaming,Li, Jian,Li, Yibiao,Liu, Jiasheng,Peng, Shiyong,Zhang, Kun

supporting information, p. 9292 - 9299 (2020/12/03)

Under catalyst-free conditions, an efficient method to synthesize 2-pyridinylamides has been developed, and the protocol uses inexpensive and readily available 2-fluoropyridine and amidine derivatives as the starting materials. Simultaneously, the copper-catalysed approach to imidazopyridine derivatives has been established with high chemoselectivity and regiospecificity. The results suggest that the nitrogen-heterocycles containing iodide substituents can also be compatible for the reaction via the cascade Ullmann-type coupling, and the nucleophilic substitution reaction provides the target products in a one-pot manner.

SYNTHESIS OF SOME 1-ALKYL-1,4-DIHYDRO-4-OXO-1,7-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS

Radl, Stanislav,Hradil, Pavel

, p. 2420 - 2429 (2007/10/02)

Reaction of substituted 2-aminopyridines IIIa, IIIb, IIIe, and IIIf with ethyl ethoxymethylene malonate provided corresponding pyridylaminomethylenemalonates Va-Vd, respectively.Thermal cyclization of Va, Vc, and Vd yielded substituted ethyl 4-hydroxy-1,7-naphthyridine-3-carboxylates VIa, VIc, and VId.Compounds VIc and VId treated with morpholine have 8-morpholino derivatives VIe and VIf.These compounds were ethylated to mixtures of N-ethylated (VIIa, VIIb) and O-ethylated products (VIIIa, VIIIb).Compound VIIIb was also prepared from ethyl 4-chloro-6-fluoro-8-morpholino-1,7-naphthyridine-3-carboxylate VIIIc and sodium ethanolate.Esters VIIa and VIIb were hydrolyzed under acidic conditions to the respective acids VIIc and VIId.

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