1188-24-5Relevant articles and documents
A novel L-amino acid ligase from Bacillus subtilis NBRC3134, a microorganism producing peptide-antibiotic rhizocticin
Kino, Kuniki,Kotanaka, Yoichi,Arai, Toshinobu,Yagasaki, Makoto
, p. 901 - 907 (2009)
L-Amino acid ligase catalyzes the formation of an α-peptide bond from unprotected L-amino acids in an ATP-dependent manner, and this enzyme is very useful in efficient peptide production. We performed enzyme purification to obtain a novel L-amino acid lig
DPP4 INHIBITOR AND PHARMACEUTICAL APPLICATION THEREOF
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Page/Page column 8-9, (2008/06/13)
The present invention provides a Dpp4 inhibitor which comprises a leucine derivative of the following formula (1) or a methionine derivative of the following formula (2): wherein each R1 and R3 represents a hydrogen atom (H) and an L-amino acid residue; R2 represents a hydroxyl group (OH), alkoxy group having 1 to 6 carbon atoms, amino group (NH2), alkylamino group having 1 to 6 carbon atoms, glycine residue, β-alanine residue, L-amino acid (except for proline, alanine and phenylalanine) residue or L-amino-acid amide (except for proline amide, alanine amide and phenylalanine amide) residue; and R4 represents a hydroxyl group (OH), alkoxy group having 1 to 6 carbon atoms, amino group (NH2), alkylamino group having 1 to 6 carbon atoms, glycine residue, β-alanine residue, L-amino acid (except for proline and alanine) residue or L-amino-acid amide (except for proline amide and alanine amide) residue. These derivatives also act as autophagy regulators.
AMINO-ACIDS AND PEPTIDES. XXI. REMOVAL OF THE NITRO-GROUP FROM
SCOPES,WALSHAW,WELFORD,YOUNG
, p. 782 - 786 (2007/10/05)
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