118829-15-5Relevant articles and documents
New 8-(trifluoromethyl)-substituted quinolones. The benefits of the 8- fluoro group with reduced phototoxic risk
Sanchez,Bridges,Bucsh,Domagala,Gogliotti,Hagen,Heifetz,Joannides,Sesnie,Shapiro,Szotek
, p. 361 - 367 (2007/10/02)
A series of 8-(trifluoromethyl)-substituted quinolones has been prepared and evaluated for in vitro and in vivo antibacterial activity, and phototolerance in a mouse phototolerance assay. These analogues were compared to the corresponding series of 6,8-di