118829-12-2Relevant articles and documents
A Dramatic Solvent Effect during Aromatic Halogen-Metal Exchanges. Different Products from Lithiation of Polyfluorobromobenzenes in Ether and THF
Bridges, Alexander J.,Patt, William C.,Stickney, Thomas M.
, p. 773 - 775 (1990)
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New 8-(trifluoromethyl)-substituted quinolones. The benefits of the 8- fluoro group with reduced phototoxic risk
Sanchez,Bridges,Bucsh,Domagala,Gogliotti,Hagen,Heifetz,Joannides,Sesnie,Shapiro,Szotek
, p. 361 - 367 (2007/10/02)
A series of 8-(trifluoromethyl)-substituted quinolones has been prepared and evaluated for in vitro and in vivo antibacterial activity, and phototolerance in a mouse phototolerance assay. These analogues were compared to the corresponding series of 6,8-di
8-trifluoromethyl quinolones as antibacterial agents
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, (2008/06/13)
A novel series of quinolone carboxylic acids for use as antibacterial agents are described. Methods for making the compounds, methods of using the compounds and compositions containing them are also described. Certain novel intermediates are also describe