1188475-55-9Relevant articles and documents
Correction to: Direct difluoromethylation of aryl halides via base metal catalysis at room temperature (Journal of the American Chemical Society (2016) 138 (2536?2539) DOI: 10.1021/jacs.6b00053)
, p. 3917 - 3917 (2017)
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Direct Difluoromethylation of Aryl Halides via Base Metal Catalysis at Room Temperature
Xu, Long,Vicic, David A.
supporting information, p. 2536 - 2539 (2016/03/12)
A stable and isolable difluoromethyl zinc reagent has been prepared through the reaction of ICF2H with diethyl zinc and DMPU. This new zinc reagent is a free-flowing solid and can be used in combination with a nickel catalyst to difluoromethylate aryl iodides, bromides, and triflates at room temperature. Such mild conditions for the catalytic difluoromethylation of these substrates are unprecedented.
Silver-catalyzed oxidative activation of benzylic C-H bonds for the synthesis of difluoromethylated arenes
Xu, Peng,Guo, Shuo,Wang, Liyan,Tang, Pingping
supporting information, p. 5955 - 5958 (2014/06/10)
A mild and catalytic method to form difluoromethylated arenes through the activation of benzylic C-H bonds has been developed. Utilizing AgNO3 as the catalyst, various arenes with diverse functional groups undergo activation/fluorination of ben
