118891-95-5 Usage
General Description
N-isopropyl-3-amino-2-(3,4-dihydroxyphenyl)-2-hydroxybicyclo(2.2.1)heptane is a chemical compound that is derived from the bicyclo(2.2.1)heptane structure and contains an isopropyl group, an amino group, and a hydroxyphenyl group. The compound is a derivative of norfenefrine, a sympathomimetic amine that acts as a vasoconstrictor. It is used in the treatment of hypotension and shock, as well as for improving blood pressure in patients with low cardiac output. The compound also has potential applications in the field of medicinal chemistry and drug development, particularly in the design of new sympathomimetic agents for cardiovascular therapy.
Check Digit Verification of cas no
The CAS Registry Mumber 118891-95-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,8,9 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 118891-95:
(8*1)+(7*1)+(6*8)+(5*8)+(4*9)+(3*1)+(2*9)+(1*5)=165
165 % 10 = 5
So 118891-95-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H23NO3/c1-9(2)17-15-10-3-4-11(7-10)16(15,20)12-5-6-13(18)14(19)8-12/h5-6,8-11,15,17-20H,3-4,7H2,1-2H3
118891-95-5Relevant articles and documents
Synthesis and Evaluation of the Pharmacological Activity of Rigid Analogues of Sympathomimetic Catecholamines Derived from Bicycloheptane
Balsamo, A.,Breschi, M. C.,Lapucci, A.,Macchia, B.,Macchia, F.,et al.
, p. 856 - 859 (2007/10/02)
endo-3-Amino-exo-2-(3,4-dihydroxyphenyl)-2-hydroxybicycloheptane (4a) and its N-isopropyl derivatives (4b) were synthesized and assayed for their adrenergic activity on various isolated preparations.Compounds 4a and 4b, tested up to a dose of 10su
