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Usage

Uses

Used in Organic Synthesis:
1,2-Bis(benzyloxy)-4-bromobenzene is used as a building block for the synthesis of various organic compounds, providing a versatile starting material for the creation of a wide range of chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,2-Bis(benzyloxy)-4-bromobenzene is used as a key intermediate in the development of new drugs, contributing to the advancement of medicinal chemistry and the discovery of novel therapeutic agents.
Used in Materials Science:
1,2-Bis(benzyloxy)-4-bromobenzene is utilized in materials science for the development of liquid crystals and polymers, playing a crucial role in the creation of innovative materials with unique properties and applications.
Used in Chemical Research:
As a chemical compound with unique structural features, 1,2-Bis(benzyloxy)-4-bromobenzene is used in research to explore new reaction pathways, mechanisms, and the synthesis of complex organic molecules, furthering the understanding of chemical processes and reactions.

Upstream product

• 2859-78-1 4-Bromoveratrole 
• 120-80-9 benzene-1,2-diol 
• 100-44-7 benzyl chloride 
• 17345-77-6 1-bromo-3,4-dihydroxybenzene 
• 100-39-0 benzyl bromide 
• 10403-73-3 1,2-di(benzyloxy)benzene 

Downstream Products

• 887259-46-3 2-[3,4-bis(benzyloxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 906665-98-3 3,4-dibenzyloxyphenyl boronic acid 
• 911694-16-1 tris[3,4-bis(benzyloxy)phenyl]boroxin 
• 32568-24-4 2(e)-<3,4-Dibenzyloxy-phenyl>-3(a)-iod-trans-decalin-2a-isocyanat; (+/-)-<2c-(3,4-Dibenzyloxy-phenyl)-3c-iod-(4ar,8at)-decahydro-(2t)-naphthyl>-isocyanat 
• 61832-59-5 N-benzyl-3-(3',4'-dibenzyloxyphenyl)-3-hydroxy-piperidine 
• 53580-18-0 3,4-bis(benzyloxy)benz-⁽¹³⁾C-aldehyde 
• 1256496-63-5 (E)-[1-⁽¹³⁾C,3-⁽¹³⁾C]-(3,5-bis(benzyloxy)-2-(3-(3',4'-bis(benzyloxy)phenyl)allyl)phenoxy)(tert-butyldimethyl)silane 
• 1256496-65-7 (1S,2S)-[1-⁽¹³⁾C,3-⁽¹³⁾C]-3-(2,4-bis(benzyloxy)-6-(tert-butyldimethylsilyloxy)phenyl)-1-(3',4'-bis(benzyloxy)phenyl)propane-1,2-diol 
• 1357910-94-1 C₄₂⁽¹³⁾C₂H₃₈O₇ 
• 1256496-71-5 5,7,3',4'-tetra-O-benzyl-[2-⁽¹³⁾C,4-⁽¹³⁾C]-(2R,3S)-catechin 
• 1256496-74-8 [2-⁽¹³⁾C,4-⁽¹³⁾C]-(2R,3S)-catechin 
• 1256496-78-2 (2R)-[2-⁽¹³⁾C,4-⁽¹³⁾C]-5,7-bis(benzyloxy)-2-(3',4'-bis(benzyloxy)chroman)-3-one 
• 1256496-81-7 5,7,3',4'-tetra-O-benzyl-[2-⁽¹³⁾C,4-⁽¹³⁾C]-(2R,3R)-epicatechin 
• 1256496-83-9 [2-⁽¹³⁾C,4-⁽¹³⁾C]-(2R,3R)-epicatechin 

Relevant academic research and scientific papers

Highly selective suppression of melanoma cells by inducible DNA cross-linking agents: Bis(catechol) derivatives

A series of bis(catechol) quaternary ammonium derivatives were designed and synthesized. We investigated their ability to cross-link DNA induced by tyrosinase and found that the o-quinone is key intermediate in the process by using the nucleophile 3-methy

Facile and divergent optimization of chromazonarol enabled the identification of simplified drimane meroterpenoids as novel pharmaceutical leads

The diversity of drimane hydroquinones was significantly expanded by the facile construction of (+)-chromazonarol relevant natural products, isomers, and analogues for the discovery of new pharmaceutical leads. The structure-activity relationship of (+)-c

INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF

Inhibitors of erythrocyte band 3 tyrosine phosphorylation, compositions comprising same, and methods of using the inhibitors and compositions to treat sickle cell diseases.

PROCESS FOR PRODUCTION OF HYDROXYTYROSOL USING ORGANOMETALLIC COMPOUNDS

Disclosed is a process for the production of a 4-(2-hydroxyalkyl)-1,2-benzenediol, comprising the steps of (a) providing protected 1,2-benzenediol having the 1,2-hydroxyl groups protected, (b) halogenating the protected 1,2-benzenediol to obtain a protected 4-halo-1,2-benzenediol having the 1,2-hydroxyl groups protected, (c) reacting, in the presence of a metal or organometallic compound, the protected 4-halo-1,2-benzenediol to protected 4-(2-hydroxyalkyl)-1,2-benzenediol having the 1,2-hydroxyl groups protected, and (d) deprotecting the protected 4-(2-hydroxyalkyl)-1,2-benzenediol to obtain the 4-(2-hydroxyalkyl)-1,2-benzenediol. Also disclosed is the use of 1,2-benzenediol for the production of hydroxytyrosol.

Synthesis of [2-13C, 4-13C]-(2R,3S)-catechin and [2-13C, 4-13C]-(2R,3R)-epicatechin

The first synthesis of doubly labeled, [2-13C, 4- 13C]-(2R,3S)-catechin 15 and [2-13C, 4- 13C]-(2R,3R)-epicatechin 18 starting from labeled 2-hydroxy-4, 6-bis(benzyloxy)acetophenone 3 and labeled 3, 4-bis(benzyloxy)-benzaldehyde 7 are described. Copyright

First total synthesis of14C-labeled procyanidin B2 - A milestone toward understanding cocoa polyphenol metabolism

The idea that foods consumed for pure pleasure could provide health benefits received much recognition in the recent years. Among these foods, cocoa and dark chocolate are particularly rich in procyanidins, one of the major dietary families of polyphenols. We developed the first asymmetric total synthesis of procyanidin B2 and applied it to the preparation of a regioselectively radiolabeled 14C-analogue, which will be used to strengthen our knowledge on the metabolism of procyanidins. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.

Total synthesis of 5,5′,6,6′-tetrahydroxy-3,3′-biindolyl, the proposed structure of a potent antioxidant found in beetroot (Beta vulgaris)

5,5′,6,6′-Tetrahydroxy-3,3′-biindolyl, the proposed structure of a phenolic antioxidant isolated from the red beetroot (Beta vulgaris), has been synthesised. The spectroscopic data of the synthetic material is not consistent with that reported for the natural product.

Enantiospecific synthesis of the antituberculosis marine sponge metabolite (+)-puupehenone. The arenol oxidative activation route.

[formula: see text] The total synthesis of the marine sesquiterpene quinone (+)-puupehenone, a promising new antituberculosis agent, was achieved in 10 steps starting from commercially available (+)-sclareolide. The key feature of this synthesis is the construction of the heterocycle via an intramolecular attack of the terpenoid-derived C-8 oxygen function onto an oxidatively activated 1,2-dihydroxyphenyl unit.