118907-66-7

Basic information

• Product Name: 2-Phenyl-butyric acid (1R,2R)-2-hydroxy-2-methyl-cyclohexyl ester
• CAS NO: 118907-66-7
• Molecular Weight: 276.376
• Mol File: 118907-66-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Phenyl-butyric acid (1R,2R)-2-hydroxy-2-methyl-cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenyl-butyric acid (1R,2R)-2-hydroxy-2-methyl-cyclohexyl ester(118907-66-7)
• EPA Substance Registry System: 2-Phenyl-butyric acid (1R,2R)-2-hydroxy-2-methyl-cyclohexyl ester(118907-66-7)

Safety Data

• Hazardous Substances Data: 118907-66-7(Hazardous Substances Data)

Upstream product

• 105928-96-9 (1R,2S)-1-methyl-1,2-cyclohexanediol 
• 1519-21-7 2-phenylbutyric anhydride 
• 6296-84-0 (1R,2R)-1-methylcyclohexane-1,2-diol 
• 96304-40-4 (R)-(+)-2-hydroxy-2-methylcyclohexanone 
• 63703-34-4 2,2-dimethoxycyclohexanol 
• 118907-58-7 2-hydroxycyclohexanone cyclic (1S,2S)-1,2-bis(methoxymethyl) ethylene acetal 
• 105873-84-5 (2R,3R)-2,3,6-Trimethyl-1,4-dioxa-spiro[4.5]decan-6-ol 
• 118907-60-1 (2R,3R)-2,3-Dimethyl-1,4-dioxa-spiro[4.5]decan-6-ol 
• 105873-74-3 2-oxo-cyclohexanone cyclic (1S,2S)-1,2-bis(methoxymethyl) ethylene acetal 
• 105873-78-7 (2S,3S,6R)-2,3-Bis-methoxymethyl-6-methyl-1,4-dioxa-spiro[4.5]decan-6-ol 
• 105873-76-5 1,2-cyclohexanedione mono-(2R,3R)-(-)-2,3-butanediol acetal 

Relevant articles and documents

Asymmetric Synthesis Using Chiral Acetals: Studies on the Nucleophilic Addition of Organometallics to Chiral α-Keto Acetals in Cyclic Systems

Four chiral cyclic α-keto acetals (3a-d) were prepared through transacetalization of the α-hydroxydimethyl acetals with (-)-(2S,3S)-1,4-dimethoxy-2,3-butanediol or (-)-(2R,3R)-2,3-butanediol and reacted with organometallic reagents (Grignard reagents and organolithium reagents).The reactions of the α-keto acetals (3a, 3b) derived from 1 and (-)-(2S,3S)-1,4-dimethoxy-2,3-butanediol with Grignard reagents proceeded in a highly diastereoselective manner.Keywords-Asymmetric synthesis; diastereoselective nucleophilic addition; chiral cyclic α-keto-acetal; (-)-(2S,3S)-1,4-dimethoxy-2,3-butanediol; (-)-(2R,3R)-2,3-butanediol; Grignard reagent; organolithium reagent