63703-34-4

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 51, p. 130, 1986 DOI: 10.1021/jo00352a002Tetrahedron Letters, 25, p. 4725, 1984 DOI: 10.1016/S0040-4039(01)81503-3

InChI:InChI=1/C8H16O3/c1-10-8(11-2)6-4-3-5-7(8)9/h7,9H,3-6H2,1-2H3

Upstream product

• 124-41-4 sodium methylate 
• 822-87-7 2-Chlorocyclohexanone 
• 67-56-1 methanol 
• 108-94-1 cyclohexanone 
• 933-40-4 cycloxexanone dimethyl ketal 
• 931-57-7 1-methoxy-cyclohex-1-ene 
• 7494-85-1 Acetic acid 2,2-dimethoxy-cyclohexyl ester 
• 533-60-8 cyclohexanone-2-ol 

Downstream Products

• 38461-13-1 2,2-dimethoxycyclohexanone 
• 17472-04-7 2-acetoxycyclohexanone 
• 6296-84-0 (1R,2R)-1-methylcyclohexane-1,2-diol 
• 105928-96-9 (1R,2S)-1-methyl-1,2-cyclohexanediol 
• 4829-02-1 (S)-(+)-2-hydroxy-2-phenylcyclohexanone 
• 96304-40-4 (R)-(+)-2-hydroxy-2-methylcyclohexanone 
• 118907-66-7 2-Phenyl-butyric acid (1S,2R)-2-hydroxy-2-methyl-cyclohexyl ester 
• 118907-66-7 2-Phenyl-butyric acid (1R,2R)-2-hydroxy-2-methyl-cyclohexyl ester 
• 105873-83-4 (2S,3S,6S)-2,3-Bis-methoxymethyl-6-phenyl-1,4-dioxa-spiro[4.5]decan-6-ol 
• 765-87-7 cyclohexane-1,2-dione 
• 226884-30-6 2-allyl-2-methoxycyclohexanone 
• 501335-68-8 1-(allyloxy)-2,2-dimethoxycyclohexane 
• 124-04-9 Adipic acid 
• 627-93-0 hexanedioic acid dimethyl ester 

Relevant academic research and scientific papers

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α-Hydroxylation of carbonyls using iodine

The α-hydroxylation of ketones and aldehydes to α-hydroxyketals mediated by iodine under basic conditions in MeOH is described. Enolates generated under the reaction conditions are iodinated and the resulting α-iodocarbonyl is transformed into the hydroxyketal. The use of iodine for this chemistry represents an economical and practical alternative to existing methods for this transformation.

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Indirect electrochemical oxidation of cyclic ketones: Influence of ring size, mediator and supporting electrolyte on the result of the reaction

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Indirect electrochemical oxidation of cyclic ketones: Strong influence of ring size on the result of the reaction

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