118965-95-0

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 94226-56-9 tert-butyl 2-(dibenzylamino)ethanoate 

Downstream Products

• 118966-00-0 (2S,3R)-3-Cyclohexyl-2-dibenzylamino-3-hydroxy-propionic acid 
• 118965-99-4 (2S,3S)-2-Dibenzylamino-3-hydroxy-nonanoic acid 
• 118965-99-4 (2S,3R)-2-Dibenzylamino-3-hydroxy-nonanoic acid 
• 118966-01-1 (2S,3S)-2-Dibenzylamino-3-hydroxy-4,4-dimethyl-pentanoic acid 
• 118966-01-1 (2S,3R)-2-Dibenzylamino-3-hydroxy-4,4-dimethyl-pentanoic acid 
• 7462-45-5 N,N-dibenzyl-DL-threonine 
• 94226-71-8 (2S,3R)-3-Cyclohexyl-2-dibenzylamino-3-hydroxy-propionic acid tert-butyl ester 
• 2043-61-0 cyclohexanecarbaldehyde 
• 94226-59-2 (2R,3S)-2-Dibenzylamino-3-hydroxy-butyric acid tert-butyl ester 
• 94226-59-2 tert-butyl (RS,RS)-2-(N,N-dibenzylamino)-3-hydroxybutanoate 
• 94226-63-8 2-Dibenzylamino-3-hydroxy-3-phenyl-propionic acid tert-butyl ester 
• 94226-67-2 (2R,3R)-2-Dibenzylamino-3-hydroxy-nonanoic acid tert-butyl ester 
• 94226-67-2 (2R,3S)-2-Dibenzylamino-3-hydroxy-nonanoic acid tert-butyl ester 
• 94226-65-0 2-Dibenzylamino-3-hydroxy-nonanoic acid methyl ester 

Relevant academic research and scientific papers

Practical and robust method for regio- and stereoselective preparation of (E)-ketene tert-butyl TMS acetals and β-ketoester-derived tert-butyl (1Z,3E)-1,3-bis(TMS)dienol ethers

(Chemical Equation Presented) We developed an efficient, practical, robust method for the regio- and stereoselective preparation of (E)-ketene trimethylsilyl acetals (KSAs) derived from tert-butyl esters 1. The reaction was performed under convenient reac

DIBENZYLAMINOACETATES AS USEFUL SYNTHETIC EQUIVALENTS OF GLYCINE IN THEi SYNTHESIS OF α-AMINO-β-HYDROXYACIDS

The stereochemical course of three new simple methodologies for the preparation of α-amino-β-hydroxyacids starting from dibenzylaminoacetates as synthetic equivalents of glycine is described.While the aldol-type condensation via lithium enolates gave results highly dependent on the aldehyde employed, producing in some cases diastereoselectivities up to 5:1 for the anti isomers, the acid-catalysed aldol condensation of silyl ketene acetals yielded predominantly syn adducts with selectivities from 5:1 to 32:1.Finally the acylation-reduction procedure gave the best results in terms of yields and stereoselectivities, affording syn isomers with excellent induction ( 13:1).