118972-96-6

Usage

Uses

Used in Pharmaceutical Industry:
1-Acetyl-3-hydroxyazetidine is used as a building block in organic synthesis for the development of new pharmaceutical compounds and natural products. Its unique molecular structure and functional groups contribute to the creation of innovative drugs and therapeutic agents.
Used in Medicinal Chemistry Research:
1-Acetyl-3-hydroxyazetidine is used as a subject of study in medicinal chemistry due to its potential applications in the development of new drugs and therapeutic agents. Its anti-inflammatory and analgesic properties make it a promising candidate for research aimed at discovering novel treatments for various conditions.
Used in Drug Discovery:
1-Acetyl-3-hydroxyazetidine is utilized in drug discovery processes as a key intermediate in the synthesis of bioactive molecules. Its unique structural features and functional groups facilitate the design and synthesis of new chemical entities with potential therapeutic benefits.

InChI:InChI=1/C5H9NO2/c1-4(7)6-2-5(8)3-6/h5,8H,2-3H2,1H3

Upstream product

• 79-22-1 methyl chloroformate 
• 45347-82-8 azetidine-3-ol 
• 75-36-5 acetyl chloride 
• 143329-27-5 N-acetyl-3-acetoxyazetidine 

Downstream Products

• 519188-47-7 1-[3-(trityloxy)-1-azetidinyl]-1-ethanone 
• 179894-05-4 N-acetylazetidin-3-one 

Relevant academic research and scientific papers

Acylative dealkylation of N-tert-butyl-3-substituted azetidines: Facile access to [1.1.0]azabicyclobutane, 3-hydroxyazetidinium hydrochloride, and 3-azetidinones

A novel acylative dealkylation of N-tert-butylazetidines and its application to the facile high-yield syntheses of [1.1.0]azabicyclobutane, 3-hydroxyazetidinium hydrochloride, and 3-azetidinones is described.

Photodimerization of N-acetyl-2-azetine: Synthesis of syn- diazatricyclooctane and anti-diazatricyclooctane (diaza-3-ladderane)

Photodimerization of N-acetyl-2-azetine to yield both possible head to head dimers with syn and anti geometries is described.

6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR

The invention relates to novel compounds of Formula I: wherein A, Y, R1, R2 and the subscript b each has the meaning as described herein and compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates, metabolites, isotopes, pharmaceutically acceptable salts, or prodrugs thereof. Compounds of Formula I and pharmaceutical compositions thereof are useful in the treatment of disease and disorders in which undesired or over-activation of NF-kB signaling is observed.

Aryloxy and aryloxyalklazetidines as antiarrhythmic and anticonvulsant agents

Methods of treating cardiac arrhythmias and convulsions in warm-blooded animas and pharmaceutical compositions therefor are disclosed. The compounds useful in the methods of treatment and compositions are represented by the formula STR1 where n is 0 to 3 and R is H, C1 -C4 alkyl or arylalkyl and Ar is phenyl or substituted phenyl.

Preparation of 3-Oxo- and 3-Ethylideneazetidine Derivatives

The preparation of 3-azetidinones with different N-substituents and their transformation to 3-ethylideneazetidines has been studied in relation with a projected synthesis of 3-ethylideneazetidine-2-carboxylic acid (= polyoximic acid; 1).The stable crystal