118975-81-8

Upstream product

• 78605-23-9 ethyl 2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane-1-acetate 
• 622-29-7 N-Benzylidenemethylamine 
• 96-10-6 diethyl aluminiumcholoride 
• 141-78-6 ethyl acetate 
• 7418-19-1 2,2,5,5-tetramethyl-1-aza-2,5-disila-cyclo-pentane 
• 25521-74-8 N-benzylidenemethylamine 
• 7646-85-7 Zinc chloride 

Downstream Products

• 118975-89-6 trans-1-methyl-3-amino-4-phenyl-2-azetidinone 

Relevant academic research and scientific papers

Meta-containing enolate compounds

Trans-β-lactams are prepared in a nearly quantitative yield by a condensation reaction of a new intermediate metal enolate and an appropriate imine. Certain new metal enolates are provided as intermediates.

STEREOSELECTIVE ONE-POT SYNTHESES OF TRANS-3-AMINO-β-LACTAMS FROM ZINC ENOLATES OF N-PROTECTED α-AMINOACID ESTERS AND IMINES

A new one-pot synthesis of 3-amino-β-lactams that is based on the condensation of simple imines with zinc enolates of disilyl protected glycine esters is reported.Isolated yields are high and a trans-selectivity is observed.

A synthesis for beta-lactams with the aid of a metal compound

Trans-β-lactams are prepared in a nearly quantative yield by a condensation reaction of a new intermediate metal enolate and an appropriate imine. Certain new metal enolates are provided as intermediates.