118989-55-2

Basic information

• Product Name: N-(4-dimethylaminophenyl)-2-(4-(3-hydroxypropyl)-1-piperazinyl)acetamide
• CAS NO: 118989-55-2
• Molecular Weight: 320.435
• Mol File: 118989-55-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-dimethylaminophenyl)-2-(4-(3-hydroxypropyl)-1-piperazinyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-dimethylaminophenyl)-2-(4-(3-hydroxypropyl)-1-piperazinyl)acetamide(118989-55-2)
• EPA Substance Registry System: N-(4-dimethylaminophenyl)-2-(4-(3-hydroxypropyl)-1-piperazinyl)acetamide(118989-55-2)

Safety Data

• Hazardous Substances Data: 118989-55-2(Hazardous Substances Data)

Upstream product

• 5317-32-8 3-(1-piperazinyl)-1-propanol 
• 38426-10-7 2-chloro-N-<(4-diethylamino)phenyl>acetamide 

Relevant articles and documents

EXPERIMENTAL ANTIULCER AGENTS: N-SUBSTITUTED 2-(4-METHYL-1-PIPERAZINYL)ACETAMIDES AS PIRENZEPINE MODELS AND SOME RELATED COMPOUNDS

Reactions of N-cyclohexyl-2-chloroacetamide, N-phenyl-2-chloroacetamide, N-(4-dimethylaminophenyl)-2-chloroacetamide, N-(2-nitrophenyl)-N-phenyl-2-chloroacetamide, its 3-nitrophenyl and 4-nitrophenyl analogues, N-(2-benzylphenyl)-2-chloroacetamide, 5-(chloroacetyl)dibenzazepine, and its 10,11-dihydro derivative with piperazine, 1-methylpiperazine, 2-(1-piperazinyl)ethanol, and 3-(1-piperazinyl)propanol resulted in compounds II, III, V -XV, XVIII, XXI, and XXIII, simple analogues of the antiulcer agent pirenzepine (I).Contributions to the syntheses and characterization of mianserin (XIX), bisnor analogue of imipramine (XXV), and pirenzepine (I) are presented.Two 2-aryl-2-(2-pyridyl)thioacetamides XXXVIII and XL were synthesized via nitriles XXXIX and XLI.Compounds XI (VUFB-17 104) and XXI (VUFB-17 113) were found to be rather effective as anti-ulcer agents and anticholinergics.