118992-35-1

Upstream product

• 118992-17-9 E,Z-8-trimethylsilyloct-6-ene-1,2-diol 
• 98-59-9 p-toluenesulfonyl chloride 
• 63922-69-0 (2-trimethylsilylethylidene)triphenylphosphorane 
• 14739-10-7 4-(2,2-dimethyl-1,3-dioxolane-4-yl)-1-butanol 
• 92121-14-7 acetonide of E,Z-8-trimethylsilyloct-6-ene-1,2-diol 
• 69891-85-6 4-(2,2-dimethyl-[1,3]-dioxolan-4-yl)-butyraldehyde 
• 106-69-4 hexane-1,2,6-triol 

Relevant academic research and scientific papers

Allylsilane Cyclisations in Organic Synthesis; Formation of a Cyclopentane via Cyclisation of an Epoxy-allylsilane

The epoxy-allylsilane (1) was prepared by two routes and cyclised stereoselectively to give the cis-cyclopentane (9) on treatment with TiCl4; equilibration of the aldehyde corresponding to (9) gave the trans-isomer in high yield.

EPOXY-SILANES IN ORGANIC SYNTHESIS

Stereoselective reactions involving functionalised β,γ-epoxysilanes and epoxide-allylsilanes provide a range of synthetically useful transformations.