1190-00-7Relevant articles and documents
Preparation method of distearoyl phosphatidylethanolamine
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Paragraph 0057; 0082-0087, (2021/03/30)
The invention provides a preparation method of distearoyl phosphatidylethanolamine, wherein the preparation method comprises the following steps: (1) under alkaline conditions, carrying out amino protection reaction on glyceryl phosphatidylethanolamine represented by a formula (II) and a compound containing an amino protection group to obtain an intermediate a represented by a formula (III); (2) under the action of a catalyst, carrying out acylation reaction on the intermediate a and stearic anhydride to obtain an intermediate b represented by a formula (IV); and (3) under an acidic condition,carrying out an amino protection group removal reaction on the intermediate b to obtain distearoyl phosphatidylethanolamine represented by a formula (V), wherein R in the formula (III), the formula (IV) and the formula (V) represents an amino protection group. The preparation method is simple to operate, high in product yield and easy for industrial production.
BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS
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, (2014/04/18)
The present invention relates to nitro-carboxylic acid (s)-containing phospholipids, to be used for coating of medical devices such as stents, catheter balloons, wound pads or surgical suture material and for bio-passivating compositions, such as rinses, waterproofing solutions, coating solutions, cryoprotection solutions, cold preservation media, lyoprotection solutions, contrast media solutions, preservation and reperfusion solutions containing these compounds as well as preparing solutions thereof and coating medical devices as well as their uses.
Monoclonal antibody recognizing phosphatidylinositol-3,4,5-triphosphate
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, (2008/06/13)
A monoclonal antibody that specifically recognizes phosphatidylinositol-3,4,5-triphosphate (PIP3) but does not cross-react with structurally similar phospholipid antigens is advantageous for PIP3-specific immunoassay. The gene in the variable regions of the monoclonal antibody has been identified, which enables producing recombinant antibodies.