119009-80-2

Upstream product

• 126862-94-0 C₄₅H₄₈N₅O₁₂PS 
• 119038-34-5 5'-O-monomethoxytrityl-3'-S-benzoyl-3'-thiothymidine 
• 119005-68-4 5′-O-(mono-p-methoxytriphenylmethyl)-3′-deoxy-3′-thiothymidine 
• 21090-30-2 3'-O-acetylthymidine 
• 130446-03-6 methanesulfonic acid (2R,3S,5R)-2-[bis(4-methoxyphenyl)phenylmethoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)tetrahydrofuran-3-yl ester 
• 142827-02-9 3'-deoxy-3'-(2,4-dinitrophenyldisulfanyl)-5'-O-(monomethoxytrityl)thymidine 

Downstream Products

• 142827-10-9 C₄₂H₄₅N₄O₁₃PS 

Relevant academic research and scientific papers

Application of the Michaelis-Arbusov Reaction to the Synthesis of Internucleoside 3'-S-Phosphorothiolate Linkages

The 5'-O-monomethoxytrityl-3'-S-(aryldisulfanyl)-3'-deoxythymidines 7 and 8 have been prepared by the reaction of 5'-O-monomethoxytrityl-3'-thiothymidine with the appropriate arenesulfenyl chloride.These disulfides undergo a Michaelis-Arbusov reaction wit

SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING 3'-THIOTHYMIDINE

A 5'-O-monomethoxytritylthymidine-3'-S-thiophosphoramidite (3) has been used to prepare oligodeoxynucleotides containing 3'-thiothymidine on a solid phase support.The intermediate thiophosphites are most efficiently oxidised using tetrabutylammonium periodate.