1190109-49-9Relevant academic research and scientific papers
BINOL derivatives-catalysed enantioselective allylboration of isatins: Application to the synthesis of (: R)-chimonamidine
Braire, Julien,Carreaux, Fran?ois,Dorcet, Vincent,Lalli, Claudia,Vidal, Jo?lle
supporting information, p. 6042 - 6046 (2020/11/04)
The asymmetric synthesis of the 3-allyl-3-hydroxyoxindole skeleton was accomplished in yields up to 99% via a metal-free and enantioselective allylation of isatins (90-96% ee) using BINOL derivatives as catalysts and an optimized allylboronate. This methodology was applied at a gram-scale to the synthesis of the natural product (R)-chimonamidine. This journal is
Chiral CNN pincer palladium(II) complexes with 2-aryl-6-(oxazolinyl) pyridine ligands: Synthesis, characterization, and application to enantioselective allylation of isatins and suzuki-miyaura coupling reaction
Wang, Tao,Hao, Xin-Qi,Huang, Juan-Juan,Wang, Kai,Gong, Jun-Fang,Song, Mao-Ping
, p. 194 - 205 (2014/02/14)
A series of chiral 2-aryl-6-(oxazolinyl)pyridine (aryl = phenyl or 1-naphthyl) ligands 2a-f were conveniently prepared from commercially available 6-bromo-2-picolinaldehyde in two steps. Reaction of 2a-f with PdCl2 in toluene in the presence of
Kinetic resolution of tertiary alcohols: Highly enantioselective access to 3-hydroxy-3-substituted oxindoles
Lu, Shenci,Poh, Si Bei,Siau, Woon-Yew,Zhao, Yu
supporting information, p. 1731 - 1734 (2013/04/10)
Enantioselective: The first highly enantioselective kinetic resolution of 3-hydroxy-3-substituted oxindoles has been developed through oxidative esterification catalyzed by a N-heterocyclic carbene (see picture). This method uses a simple procedure and provides 3-hydroxy-oxindoles with various substituents at the 3-position in excellent enantiopurity. S=selectivity. Copyright
