119020-03-0

Basic information

• Product Name: (S)-2-(Aminomethyl)-1-Cbz-pyrrolidine
• Synonyms: 2-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER;(+/-)-2-(AMINOMETHYL)-1-N-CBZ-PYYROLIDINE;1-N-CBZ-2-(AMINOMETHYL)PYRROLIDINE;1-CBZ-2-AMINOMETHYL PYRROLIDINE;4-AMINOMETHYL-1-N-CBZ-PIPERIDINE;4-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER;4-(AMINOMETHYL)PIPERIDINE, N-CBZ PROTECTED;BUTTPARK 93\50-51
• CAS NO: 119020-03-0
• Molecular Formula: C₁₃H₁₈N₂O₂
• Molecular Weight: 234.29
• Product Categories: Pyrrole&Pyrrolidine&Pyrroline
• Mol File: 119020-03-0.mol

Chemical Properties

• Boiling Point: 370.5 °C at 760 mmHg
• Flash Point: 177.9 °C
• Appearance: /
• Density: 1.155 g/cm³
• Vapor Pressure: 1.1E-05mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: Room temperature.
• PKA: 9.91±0.29(Predicted)
• CAS DataBase Reference: (S)-2-(Aminomethyl)-1-Cbz-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(Aminomethyl)-1-Cbz-pyrrolidine(119020-03-0)
• EPA Substance Registry System: (S)-2-(Aminomethyl)-1-Cbz-pyrrolidine(119020-03-0)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-39
• Hazardous Substances Data: 119020-03-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-(Aminomethyl)-1-Cbz-pyrrolidine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable building block for the development of new drugs, particularly those targeting the central nervous system.
Used in Chemical Synthesis:
(S)-2-(Aminomethyl)-1-Cbz-pyrrolidine is used as a reagent in the preparation of specific chemical compounds, such as trifluoro-N-[(S)-pyrrolidinylmethyl]methanesulfonamide. Its chiral nature and functional groups allow for selective reactions and the formation of complex molecules with potential applications in various fields.

InChI:InChI=1/C13H18N2O2/c14-9-12-7-4-8-15(12)13(16)17-10-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10,14H2

Upstream product

• 141774-67-6 (S)-benzyl 2-(azidomethyl)pyrrolidine-1-carboxylate 
• 34079-31-7 Z-Pro-NH₂ 
• 6216-63-3 N-Cbz-Prolinol 
• 72500-24-4 (2S)-2-(4-methylphenylsulfonyloxymethyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 501-53-1 benzyl chloroformate 
• 147-85-3 L-proline 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 63808-36-6 (2S)-2-cyanopyrrolidine-1-carboxylic acid benzyl ester 

Downstream Products

• 782495-19-6 (S)-2-(trifluoromethanesulfonylaminomethyl)-1-N-nemzyloxycarbonyl-pyrrolidine 
• 782495-18-5 N-(((2S,4R)-4-(tert-butyldimethylsilyloxy)pyrrolidin-2-yl)methyl)-1,1,1-trifluoromethanesulfonamide 
• 1172596-79-0 benzyl (S)-2-(isothiocyanatomethyl)pyrrolidine-1-carboxylate 
• 1206881-76-6 (S)-benzyl 2-((N,N-diphenylphosphinamido)methyl)pyrrolidine-1-carboxylate 
• 1321848-92-3 benzyl (S)-2-((3-(3,5-bis(trifluoromethyl)phenyl)thioureido)methyl)pyrrolidine-1-carboxylate 
• 1393378-00-1 (S)-2-((pyridin-2-ylmethylamino)methyl)-1-N-Cbz-pyrrolidine 
• 1393378-01-2 (S)-2-((6-methyl-pyridin-2-ylmethylamino)methyl)-1-N-Cbz-pyrrolidine 
• 1393378-02-3 (S)-benzyl 2-((methyl(pyridin-2-ylmethyl)amino)methyl)pyrrolidine-1-carboxylate 
• 1393378-03-4 (S)-benzyl 2-((methyl((6-methylpyridin-2-yl)methyl)amino)methyl)pyrrolidine-1-carboxylate 
• 1419208-74-4 benzyl (S)-2-(pivalamidomethyl)pyrrolidine-1-carboxylate 
• 1419208-73-3 benzyl (S)-2-(benzamidomethyl)pyrrolidine-1-carboxylate 
• 853934-65-3 (S)-N-(pyrrolidin-2-ylmethyl)benzamide 
• 1474047-58-9 benzyl (S)-2-({(1S,2S,3R,5S)-2-[(tert-butoxycarbonyl)amino]-2,6,6-trimethylbicyclo[3.1.1]heptan-3-ylcarboxamido}methyl)pyrrolidine-1-carboxylate 
• 1599474-00-6 (S)-benzyl 2-(((3aR,5S,6R,6aR)-6-azido-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carboxamido)methyl)pyrrolidine-1-carboxylate 

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ORGANOCATALYSTS AND METHODS OF USE IN CHEMICAL SYNTHESIS

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