119020-89-2Relevant articles and documents
Chitosan: An efficient recyclable catalyst for transamidation of carboxamides with amines under neat conditions
Nageswara Rao, Sadu,Chandra Mohan, Darapaneni,Adimurthy, Subbarayappa
, p. 4122 - 4126 (2014)
A novel chitosan-catalyzed transamidation of carboxamides with amines under solvent-free conditions is described. A series of amide derivatives as well as more challenging aryl and alkyl amines with long-chain alkyl substituents could be selectively converted into the corresponding transamidation products, which are frequently found in biologically active compounds and pharmaceuticals. Under similar reaction conditions benzo[d]heterocycles were also obtained via a one-pot synthesis through transamidation and subsequent dehydration. Recyclability of chitosan was demonstrated, with quantitative yields of products obtained without any loss of catalytic activity. the Partner Organisations 2014.
A general and selective copper-catalyzed reduction of secondary amides
Das, Shoubhik,Join, Benoit,Junge, Kathrin,Beller, Matthias
supporting information; experimental part, p. 2683 - 2685 (2012/04/04)
In situ-generated cationic copper/pybox catalyst systems allow for the selective reduction of secondary amides into the corresponding amines under mild conditions. This novel protocol has a wide substrate scope and shows good functional group tolerance. The Royal Society of Chemistry 2012.
