1190308-63-4Relevant academic research and scientific papers
Biomimetic asymmetric 1,3-dioplar cycloaddition: Amino acid precursors in biosynthesis serve as latent azomethine ylides
Guo, Chang,Song, Jin,Gong, Liu-Zhu
supporting information, p. 2676 - 2679 (2013/07/19)
The first asymmetric catalytic biomimetic three-component 1,3-dipolar cycloaddition of α-keto esters and benzylamine with electron-deficient olefins, inspired by the transamination of α-keto acids involving pyridoxal phosphate (PLP)-dependent enzymes in biological systems, giving several families of structurally diverse pyrrolidine derivatives in high yields and excellent enantioselectivities (up to 99% ee) under mild conditions is described.
Organocatalytic synthesis of spiro[pyrrolidin-3,3′-oxindoles] with high enantiopurity and structural diversity
Chen, Xiao-Hua,Wei, Qiang,Luo, Shi-Wei,Xiao, Han,Gong, Liu-Zhu
supporting information; experimental part, p. 13819 - 13825 (2009/12/29)
The privileged spiro[pyrrolidin-3,3′-oxindole] derivatives exhibit important biological activities. An enantioselective organocatalytic approach to the rapid synthesis of spiro[pyrrolidin-3,3′-oxindole] derivatives with high enantiopurity and structural d
